ReviewEye (London, England)2025
CAIRS and nomograms: a narrative review.
Review in Eye (London, England), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
2 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Corneal Allogeneic Intrastromal Ring Segments for Treating Keratoconus-Systematic Review and Meta-Analysis.Medicina (Kaunas, Lithuania) · 2026Pooled it
- Management of astigmatism in keratoconus with therapeutic refractive surgery.Frontiers in medicine · 2026Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
CAIRS (Corneal Allogeneic Intrastromal Ring Segments) is an emerging new treatment for keratoconus that involves implantation of allogeneic corneal tissue into the periphery of the keratoconic cornea, resulting in flattening of the cone, regularisation of the central cornea, and ultimately, improved vision. Published results have been encouraging and consequently, the procedure is gaining significant traction around the world. Several nomograms have been developed to predict visual outcomes and improve accuracy and predictability. We review and compare the results of the different nomograms (e.g. how they differ in segment preparation, sizing, and placement) and delve into the key discussion points associated with the procedure, which we hope will aid the reader in gaining a greater understanding of the procedure and allow them to plan their own CAIRS procedure, in what is a rapidly evolving field.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.