Evidence map›Paper›PMID 41023383›Full record

ArticleScientific reports2025

Chroococcus turigidus, a novel cyanobacterial source for l-sparaginase production.

Reham Gamal, Esmail M El-Fakharany, Khaled N M Elsayed, Amany Salama El Sharkawy, Nader Saad Elsayed, Ola Kh Shalaby

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Scientific reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Reham GamalNational Institute of Oceanography and Fisheries, NIOF, Cairo, Egypt.
Esmail M El-FakharanyProtein Research Department, Genetic Engineering and Biotechnology Research Institute (GEBRI), City of Scientific Research and Technological Applications (SRTA-City), New Borg El-Arab, Alexandria, 21934, Egypt.
Khaled N M ElsayedBotany and Microbiology Department, Faculty of Science, Beni-Suef University, Beni-Suef, 62511, Egypt.
Amany Salama El SharkawyNational Institute of Oceanography and Fisheries, NIOF, Cairo, Egypt.
Nader Saad ElsayedSoil and Agricultural Chemistry Department, Faculty of Agriculture (Saba-Basha), Alexandria University, Alexandria, Egypt.
Ola Kh ShalabyNational Institute of Oceanography and Fisheries, NIOF, Cairo, Egypt. ola_shalaby2012@yahoo.com.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The anti-leukemic drug enzyme L-asparaginase is highly sought for its potential in treating various solid tumors; as well as its application in food production for mitigation of the carcinogenic acrylamide. Marine microalgae are well known for their diverse bioactive products and ease of cultivation, making them ideal candidates for large-scale production. Seven marine microalgae were isolated based on their L-asparaginase production, and the isolate Chroococcus turigidus was identified as the highest producer, yielding 212.413 IU/ml. The in-vitro anticancer activity of the algal extract was evaluated against breast carcinoma (MDA) and hepatoma (HepG-2) cell lines with comparison to normal human skin fibroblast (HSF) cell lines. The IC

Indexed as

Antineoplastic AgentsAsparaginaseCyanobacteriaCell Line, TumorHep G2 CellsHumansMicroalgaeAntineoplastic AgentsAsparaginaseAnti-cancerAsparaginaseChroococcus turigidusMarine microalgae

Identifiers

PMID41023383
PMCPMC12479834

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.