ArticleGeroScience2026
Surface-based morphometry reveals divergent aging trajectories in veterans with and without traumatic brain injury.
Article in GeroScience, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
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Who cites it
1 citing paper in PubMed.
- MRI-based cortical morphometry in traumatic brain injury: a pilot longitudinal study.Neuroradiology · 2026Article
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Authors and funding
6 authors.
Funding
Abstract
This study investigates how traumatic brain injury (TBI) alters cortical aging by comparing cortical thickness (CT) and surface area (SA) in 34 brain regions between TBI survivors and age-matched controls. Using a cross-sectional retrospective design, 105 Vietnam Veterans (32 with moderate-to-severe TBI, 73 controls) were analyzed via surface-based morphometry. Principal Component Analysis (PCA) reduced dimensionality, and Multivariate Analysis of Covariance tested group differences while controlling for age, education, depression, Post-Traumatic Stress Disorder, and intracranial volume. Findings revealed divergent morphometric signatures of aging: the proportion of SA variance explained by the first principal component (PC1) was lower in the TBI cohort compared to controls, particularly in parietal and limbic regions. Conversely, CT variance explained by PC1 was higher in TBI compared to controls, with fewer factor loadings in frontal and occipital regions, suggesting differential structural aging patterns due to TBI. Regression analysis demonstrated a stronger association of SA with age in TBI (R
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