Evidence map›Paper›PMID 41023172›Full record

ArticleInternational journal of impotence research2025

Pre-spermatorrhea state: a novel therapeutic paradigm for the management of non-organic delayed ejaculation and anejaculation.

Dawei Gao, Wenxiu Zhang, Chuyu Li, Yihan Jin, Weimin Deng, Dalin Sun, Baofang Jin

Abstract readLetter
PubMed Publisher
In one paragraph

Article in International journal of impotence research, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Dawei Gao *Faculty of Chinese Medicine, Macau University of Science and Technology, Macau SAR, China.ORCID http://orcid.org/0000-0001-8737-1071
Wenxiu Zhang *Department of Tranditional Chinese Medicine, Qinghai University Medical College, Xining, China.ORCID http://orcid.org/0000-0002-0212-9401
Chuyu LiFaculty of Chinese Medicine, Macau University of Science and Technology, Macau SAR, China.
Yihan JinFaculty of Chinese Medicine, Macau University of Science and Technology, Macau SAR, China.
Weimin DengAndrology Department of Integrative Medicine, Zhongda Hospital, Southeast University, Nanjing, China.
Dalin SunAndrology Department of Integrative Medicine, Zhongda Hospital, Southeast University, Nanjing, China. daling11@126.com.ORCID http://orcid.org/0000-0002-1442-9962
Baofang JinExternal Medicine in Chinese Medicine Department, The Chinese Medicine Hospital of Hong Kong, Hong Kong SAR, China. hexiking@126.com.ORCID http://orcid.org/0000-0002-5604-2897

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Delayed ejaculation (DE) and anejaculation (AE) pose significant clinical challenges in andrology and sexual medicine, with no universally effective or standardized treatments currently available. In clinical practice, management strategies are primarily empirical. Drawing inspiration from the physiological mechanisms underlying nocturnal emissions, we propose a novel therapeutic approach for non-organic DE and AE. This method aims to facilitate ejaculation by enhancing seminal vesicle fluid secretion, thereby increasing prostatic urethral pressure during sexual activity. To this end, we administered Yangjing Capsules, a traditional Chinese herbal formulation with kidney-tonifying properties, to promote seminal vesicles secretory function. Preliminary clinical findings demonstrated an efficacy rate of 83.3% in the treatment group, compared to 40% in the control group treated with ephedrine tablets (RR = 2.083; 95% CI:1.331-3.626; P = 0.0016). We anticipate that this strategy may offer a novel option for the clinical management of non-organic DE and AE and provide new insights into therapeutic development in this field.

Identifiers

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.