Evidence map›Paper›PMID 41023135›Full record

ArticleScientific reports2025

First detection and genetic characterization of atypical Porcine pestivirus in pigs, Thailand.

Sana Shahid, Chaitawat Sirisereewan, Eaint Min Phyu, Chanakarn Nasamra, Supassama Chaiyawong, Sirawit Pagdepanichkit, Somsak Pakpinyo, Alongkorn Amonsin, Kamonpan Charoenkul

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Scientific reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Sana ShahidCenter of Excellence for Emerging and Re-emerging Infectious Diseases in Animals, Faculty of Veterinary Science, Chulalongkorn University, Bangkok, Thailand.
Chaitawat SirisereewanCenter of Excellence for Emerging and Re-emerging Infectious Diseases in Animals, Faculty of Veterinary Science, Chulalongkorn University, Bangkok, Thailand.
Eaint Min PhyuDepartment of Veterinary Public Health, Faculty of Veterinary Science, Chulalongkorn University, Bangkok, 10330, Thailand.
Chanakarn NasamraCenter of Excellence for Emerging and Re-emerging Infectious Diseases in Animals, Faculty of Veterinary Science, Chulalongkorn University, Bangkok, Thailand.
Supassama ChaiyawongCenter of Excellence for Emerging and Re-emerging Infectious Diseases in Animals, Faculty of Veterinary Science, Chulalongkorn University, Bangkok, Thailand.
Sirawit PagdepanichkitDepartment of Veterinary Public Health, Faculty of Veterinary Science, Chulalongkorn University, Bangkok, 10330, Thailand.
Somsak PakpinyoCenter of Excellence for Emerging and Re-emerging Infectious Diseases in Animals, Faculty of Veterinary Science, Chulalongkorn University, Bangkok, Thailand.
Alongkorn AmonsinCenter of Excellence for Emerging and Re-emerging Infectious Diseases in Animals, Faculty of Veterinary Science, Chulalongkorn University, Bangkok, Thailand.
Kamonpan CharoenkulCenter of Excellence for Emerging and Re-emerging Infectious Diseases in Animals, Faculty of Veterinary Science, Chulalongkorn University, Bangkok, Thailand. Kamonpan.C@chula.ac.th.

Funding

Thailand Science Research and Innovation Fund Chulalongkorn University [FOOD_FF_68_215_3100_019]the Chulalongkorn University' TSRI Fundamental Fund (HEA68310011), the Center of Excellence for Emerging and Re-emerging Infectious Diseases in Animals (CUEIDAs), HEA68310011
6 · The paper itself

Abstract

Atypical Porcine Pestivirus (APPV) is an emerging pathogen in pigs. The virus causes diseases associated with neurological disorders, such as congenital tremors (CT) Type A-II in piglets, leading to economic losses in the swine industry. This study investigated an outbreak of Atypical Porcine Pestivirus (APPV) on a commercial pig farm in eastern of Thailand from November 2023 to July 2024. Our results showed APPV positive in 14.18% (39/275). APPV was highly detected in nursery pigs at 40.00% (12/30) with a statistically significant (P < 0.05) association between age and APPV infection. Thai-APPVs (n = 9) were characterized by complete genome sequencing. Phylogenetic analysis of the whole genome of APPVs showed that Thai-APPVs belonged to APPV-Clade I. Moreover, the Thai-APPVs were clustered into a distinct subclade of APPV-Clade I, namely the Thai subclade, suggesting potential geographical adaptation. In conclusion, this study is the first to report the detection and genetic characterization of APPVs in a pig farm in Thailand, enhancing the understanding of its epidemiology and genetic diversity. Our findings highlight the need for APPV surveillance, particularly in young pigs, to facilitate early interventions and control measures.

Indexed as

PestivirusPestivirus InfectionsSwine DiseasesAnimalsDisease OutbreaksGenetic VariationGenome, ViralPhylogenySwineThailandWhole Genome SequencingAPPVAtypical pestivirusGenetic characterizationPigsThailand

Identifiers

PMID41023135
PMCPMC12479871

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.