Evidence map›Paper›PMID 41023074›Full record

ArticleScientific reports2025

Development and evaluation of a novel capillary blood collection method for decentralized therapeutic drug monitoring using the True Dose kit.

Nektarios Komninos, Serena De Chiara, Antonio Checa, Oscar Wiklander, Per Rydberg, Elham Hedayati

Abstract read
In one paragraph

Article in Scientific reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Nektarios KomninosTrue Dose AB, Stockholm, Sweden.
Serena De ChiaraTrue Dose AB, Stockholm, Sweden.
Antonio ChecaUnit of Integrative Metabolomics, Institute of Environmental Medicine, Karolinska Institute, 171 77, Stockholm, Sweden.
Oscar WiklanderUnit for Biomolecular and Cellular Medicine, Department of Laboratory Medicine, Karolinska Institutet, Stockholm, Sweden.
Per RydbergTrue Dose AB, Stockholm, Sweden.
Elham HedayatiDepartment of Oncology-Pathology, Karolinska Institute, 171 77, Stockholm, Sweden. elham.hedayati@ki.se.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Interindividual variability in epirubicin exposure limits the efficacy of standard chemotherapy dosing based on body surface area (BSA) in breast cancer. This study evaluated a novel liquid-based capillary microsampling technology, True Dose

Indexed as

Blood Specimen CollectionBreast NeoplasmsDrug MonitoringEpirubicinCapillariesChromatography, LiquidFemaleHumansMiddle AgedReproducibility of ResultsTandem Mass SpectrometryEpirubicinAnthracyclinesBlood specimen collection/methodsBreast neoplasms/drug therapyCapillary blood samplingEpirubicinMass spectrometry/methods

Identifiers

PMID41023074
PMCPMC12480760

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.