Trial reportScientific reports2025
Pharmacist-led behavioral change intervention improves adherence and clinical outcomes among hemodialysis patients.
Trial report in Scientific reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06744738 (Pharmacist-led Intervention on Hemodialysis Patients' Therapy Adherence), which is not on this map. Not yet cited in PubMed.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Pharmacist-led Intervention on Hemodialysis Patients' Therapy Adherence
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4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Improving adherence enhances therapeutic outcomes in hemodialysis patients; several approaches, including behavioral interventions, were utilized to improve adherence. Examine the effect of a pharmacist-led behavioral change technique (PL-BCT) intervention on hemodialysis patients' adherence to their complex therapeutic regimen and physical indices. Parallel-group, cluster-randomized, controlled trial, in which the patients were divided into usual care and PL-BCT groups. The intervention was developed based on the Behavior Change Technique Taxonomy (v1). Adherence was assessed using the End-Stage Renal Disease Adherence Questionnaire (ESRD-AQ). After one month of intervention, the PL-BCT significantly increased the total adherence score compared to usual care (950.0 vs. 825.0). Good adherence rate was higher in the PL-BCT group (42.1% vs. 14.7%). The serum phosphate level (5.83 ± 0.90 vs. 5.84 ± 1.04 mEq/L) and interdialytic weight gain (2.0 vs. 2.9 kg) significantly declined in the PL-BCT compared to usual care. In the unadjusted analysis of the relationship between the intervention of good adherence, there was a 4.592-fold increase in the odds of achieving good adherence in the PL-BCT group compared to usual care OR (95%CI): 4.592 (1.662-12.686), p-value = 0.003; this strong association was maintained in the multivariate analysis. The findings of this study suggest that BCTs support adherence among hemodialysis patients and improve certain clinical indices.Trial Registration The clinical trial registration number is NCT06744738, and the registration date is December 20, 2024.
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