Evidence map›Paper›PMID 41022980›Full record

ArticleScientific reports2025

Preliminary study on the treatment of acute angle closure glaucoma with high intensity focused ultrasound cycloplasty.

Wei Wang, Chunmiao Wang, Yi Zhou, Shuxi Yan, Xiangji Li, Lin Xie

Abstract read
In one paragraph

Article in Scientific reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Wei WangDepartment of Ophthalmology, the Third Affiliated Hospital of Chongqing Medical University, Chongqing, China.
Chunmiao WangChongqing Aier Eye Hospital, Chongqing, China.
Yi ZhouChongqing Aier Eye Hospital, Chongqing, China.
Shuxi YanChongqing Aier Eye Hospital, Chongqing, China.
Xiangji LiDepartment of Ophthalmology, the Third Affiliated Hospital of Chongqing Medical University, Chongqing, China.
Lin XieDepartment of Ophthalmology, the Third Affiliated Hospital of Chongqing Medical University, Chongqing, China. xielin@hospital.cqmu.edu.cn.

Funding

Aier Eye Hospital Group Scientific Research Fund AGF2306D04
6 · The paper itself

Abstract

High-intensity focused ultrasound cycloplasty (UCP) can effectively reduce intraocular pressure in glaucoma patients. This work aimed to analyze the efficacy, safety, and mechanism of UCP in treating acute angle-closure glaucoma. We collected and retrospectively analyzed the preoperative and postoperative clinical data of 16 cases (16 eyes) with acute angle-closure glaucoma, including the number of sectors activated, intraocular pressure (IOP), central anterior chamber depth (ACD), lens zonule length (LZL), ciliary muscle thickness (CMT), and trabecular-ciliary process angle (TCA). Of the 16 eyes, one received a single UCP procedure with 8 sectors, and the others with 10 sectors. The mean IOP at follow-up time points after UCP was significantly lower than before UCP. The mean ACD at follow-up time points after UCP was significantly higher than before UCP. The mean LZL in the superior, inferior, nasal, and temporal quadrants on postoperative day 1, week 1, and month 1 was significantly shorter than that before UCP. The mean CMT in the superior, inferior, and nasal quadrants on postoperative day 1 and in the superior and inferior quadrants on postoperative week 1 were significantly larger than those before UCP. The mean TCA in the temporal quadrant on postoperative month 3 was significantly smaller than that before UCP. In conclusion, UCP is safe and effective in treating acute angle-closure glaucoma. The special mechanism of lowering IOP after UCP may be attributed to the increased depth of the central anterior chamber and the reopening of some non-adhesive closed angles.

Indexed as

Glaucoma, Angle-ClosureHigh-Intensity Focused Ultrasound AblationAcute DiseaseAgedFemaleHumansIntraocular PressureMaleMiddle AgedRetrospective StudiesTreatment OutcomeAcute angle-closure glaucomaAnterior chamber depthIntraocular pressureTrabecular-ciliary process angleUltrasound cycloplasty

Identifiers

PMID41022980
PMCPMC12480053

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.