Evidence map›Paper›PMID 41022740›Full record

ArticleNature communications2025

Integration of diagnostics for Strongyloides stercoralis into the soil-transmitted helminths control programme in Rwanda.

Eliah Shema, Francesca Tamarozzi, Jean Bosco Mbonigaba, Salvatore Scarso, Cristina Mazzi, Paul Gasana, Benon Turatsinze, Leonard Uwayezu, Delphine Mukamigambi, Henri Desire Uwayo and 4 more

Abstract read
In one paragraph

Article in Nature communications, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. An Agar-Free, Glass Bead-Based Method for the Culture ofDiagnostics (Basel, Switzerland) · 2026
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors.

Eliah ShemaSchool of Health Sciences, College of Medicine and Health Sciences, University of Rwanda, Kigali, Rwanda.
Francesca TamarozziDepartment of Infectious, Tropical Diseases and Microbiology, IRCCS Sacro Cuore Don Calabria, Negrar di Valpolicella, Verona, Italy.
Jean Bosco MbonigabaNeglected Tropical Diseases and Other Parasitic Diseases Unit, Rwanda Biomedical Center, Ministry of Health, Kigali, Rwanda.
Salvatore ScarsoDepartment of Infectious, Tropical Diseases and Microbiology, IRCCS Sacro Cuore Don Calabria, Negrar di Valpolicella, Verona, Italy.
Cristina MazziClinical Research Unit, IRCCS Sacro Cuore Don Calabria, Negrar di Valpolicella, Verona, Italy.ORCID http://orcid.org/0000-0002-4561-3447
Paul GasanaSchool of Health Sciences, College of Medicine and Health Sciences, University of Rwanda, Kigali, Rwanda.
Benon TuratsinzeDepartment of Biomedical Laboratory Sciences, University of Rwanda, Kigali, Rwanda.ORCID http://orcid.org/0009-0007-4463-4629
Leonard UwayezuNeglected Tropical Diseases and Other Parasitic Diseases Unit, Rwanda Biomedical Center, Ministry of Health, Kigali, Rwanda.
Delphine MukamigambiNeglected Tropical Diseases and Other Parasitic Diseases Unit, Rwanda Biomedical Center, Ministry of Health, Kigali, Rwanda.
Henri Desire UwayoNation Reference Laboratory Division, Rwanda Biomedical Centre, Kigali, Rwanda.
Noel GahamanyiNation Reference Laboratory Division, Rwanda Biomedical Centre, Kigali, Rwanda.
Ladislas NshimiyimanaNeglected Tropical Diseases and Other Parasitic Diseases Unit, Rwanda Biomedical Center, Ministry of Health, Kigali, Rwanda.
Nadine RujeniSchool of Health Sciences, College of Medicine and Health Sciences, University of Rwanda, Kigali, Rwanda.
Dora BuonfrateDepartment of Infectious, Tropical Diseases and Microbiology, IRCCS Sacro Cuore Don Calabria, Negrar di Valpolicella, Verona, Italy. dora.buonfrate@sacrocuore.it.ORCID http://orcid.org/0000-0003-0108-6822

Funding

Ministero della Salute (Ministry of Health, Italy) 5 x milleMinistero della Salute (Ministry of Health, Italy) Ricerca corrente L2P12
6 · The paper itself

Abstract

The WHO recently issued guidelines for public health control of Strongyloides stercoralis in endemic areas. We aimed to evaluate the feasibility of implementing the WHO recommendations in Rwanda, and our secondary objective was to estimate S. stercoralis prevalence. We conducted a community-based cross-sectional study in two Rwandan districts (Gisagara and Rubavu) including a training session focused on diagnostics for S. stercoralis: parasitological assays (Baermann and agar plate culture, APC) and a novel rapid diagnostic test (RDT). Technicians' perceptions of each assay were evaluated via a questionnaire; 1,415 individuals were screened. A critical aspect of the parasitological assays was the length of training, but there was no issues with RDT implementation. Based on the combination of Baermann and APC diagnostics, prevalence was 1.1% (95% CI 0.5-2.3) in Gisagara, and 3.9% (95% CI 2.6-5.7) in Rubavu, which was similar for the RDT. Overall, we found the implementation of S. stercoralis-specific tests was feasible, though intense training was crucial.

Indexed as

SoilStrongyloides stercoralisStrongyloidiasisAdolescentAdultAnimalsChildChild, PreschoolCross-Sectional StudiesFecesFemaleHumansMaleMiddle AgedPrevalenceRwandaSoil

Identifiers

PMID41022740
PMCPMC12480574

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.