Evidence map›Paper›PMID 41022577›Full record

ArticlePlant physiology2025

ALMT12 interacts with and inhibits SLAC1 to modulate stomatal movements and enhance plant biomass.

Ping Lin, Hui Zhou, Qing Zhao, Liumei Li, Jiamei Liu, Zhuoran Hu, Yunxin Luo, Cuizhu Feng, Yu Long

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Plant physiology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Ping LinState Key Laboratory of Crop Stress Adaptation and Improvement, School of Life Sciences, Henan University, Kaifeng 475001, China.ORCID 0009-0004-5751-3277
Hui ZhouState Key Laboratory of Crop Stress Adaptation and Improvement, School of Life Sciences, Henan University, Kaifeng 475001, China.ORCID 0000-0001-6384-4479
Qing ZhaoState Key Laboratory of Crop Stress Adaptation and Improvement, School of Life Sciences, Henan University, Kaifeng 475001, China.
Liumei LiState Key Laboratory of Crop Stress Adaptation and Improvement, School of Life Sciences, Henan University, Kaifeng 475001, China.
Jiamei LiuState Key Laboratory of Crop Stress Adaptation and Improvement, School of Life Sciences, Henan University, Kaifeng 475001, China.ORCID 0009-0008-8872-4869
Zhuoran HuState Key Laboratory of Crop Stress Adaptation and Improvement, School of Life Sciences, Henan University, Kaifeng 475001, China.ORCID 0009-0008-1760-080X
Yunxin LuoState Key Laboratory of Crop Stress Adaptation and Improvement, School of Life Sciences, Henan University, Kaifeng 475001, China.
Cuizhu FengState Key Laboratory of Crop Stress Adaptation and Improvement, School of Life Sciences, Henan University, Kaifeng 475001, China.
Yu LongState Key Laboratory of Crop Stress Adaptation and Improvement, School of Life Sciences, Henan University, Kaifeng 475001, China.ORCID 0000-0001-7490-9581

Funding

National Natural Science Foundation of China 32270312
6 · The paper itself

Abstract

Stomata are pores that control carbon dioxide (CO2) and water exchange by modulating their aperture in response to different environmental and internal signals. The Slow-type SLOW ANION CHANNEL-ASSOCIATED 1 (SLAC1) and Rapid-type ALUMINUM-ACTIVATED MALATE TRANSPORTER 12 (ALMT12) anion channels mediate anion efflux in guard cells to promote stomatal closure. These channels were previously thought to function as 2 independent anion-permeable pores differing in their activation kinetics, voltage dependence, and anion selectivity. In this study, we found that ALMT12 interacts with and represses SLAC1 anion permeability in Xenopus oocytes and Arabidopsis (Arabidopsis thaliana) guard cells. This channel-channel regulatory mechanism modulates stomatal movements under high CO2 conditions and enhances plant biomass.

Indexed as

ArabidopsisArabidopsis ProteinsBiomassMembrane ProteinsOrganic Anion TransportersPlant StomataAnimalsCarbon DioxideOocytesProtein BindingXenopus laevisArabidopsis ProteinsCarbon DioxideMembrane ProteinsOrganic Anion TransportersSLAC1 protein, Arabidopsis

Identifiers

PMID41022577
PMCPMC12530098

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.