Evidence map›Paper›PMID 41022519›Full record

ArticleThe British journal of general practice : the journal of the Royal College of General Practitioners2026

Learning from end-of-life injectable medication patient safety incidents in the community: a mixed-methods analysis.

Ben Bowers, Sioned Gwyn, Sarah Yardley, Stuart Hellard, P John Clarkson, Isobel J McFadzean, Kristian Pollock, Stephen Barclay, Andrew Carson-Stevens

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Article in The British journal of general practice : the journal of the Royal College of General Practitioners, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Ben BowersPrimary Care Unit, Department of Public Health and Primary Care, University of Cambridge, Cambridge, UK bb527@medschl.cam.ac.uk.ORCID 0000-0001-6772-2620
Sioned GwynDivision of Population Medicine, Cardiff University, Cardiff, UK.
Sarah YardleyDivision of Population Medicine, Cardiff University, Cardiff, UK.ORCID 0000-0002-1645-642X
Stuart HellardDivision of Population Medicine, Cardiff University, Cardiff, UK.
P John ClarksonDepartment of Engineering, University of Cambridge, Cambridge, UK.ORCID 0000-0001-8018-7706
Isobel J McFadzeanDivision of Population Medicine, Cardiff University, Cardiff, UK.ORCID 0000-0001-9766-2681
Kristian PollockSchool of Health Sciences, University of Nottingham, Nottingham, UK.ORCID 0000-0002-6836-8595
Stephen BarclayPrimary Care Unit, Department of Public Health and Primary Care, University of Cambridge, Cambridge, UK.ORCID 0000-0002-4505-7743
Andrew Carson-StevensMarie Curie Research Centre, Division of Population Medicine, Cardiff University, Cardiff, UK.ORCID 0000-0002-7580-7699

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundProcesses to implement injectable end-of-life symptom control medications in the community are complex and can have an adverse impact on patient safety. Recurring patient safety incident types and their contributory factors remain underrecognised, inhibiting system-wide learning.

aimTo understand injectable end-of-life symptom control medication incidents, their contributory factors, the impact on patients/families, and identify priority areas for improving safe, effective, and timely care. DESIGN AND

settingMixed-methods analysis of nationally reported injectable medication patient safety incidents involving adults in the community in England and Wales between 2017 and 2022.

methodA stratified random sample of 2150 incidents from the National Reporting and Learning System were screened for eligibility. Incidents that involved end-of-life injectable medications in the community were included and analysed. Deductive coding was undertaken to classify incident types, the contributory factors involved, the impact on the patient, and harm severity. An iterative thematic analysis was then conducted to identify patterns between recurring incident types and contributory factors.

resultsIn total, 419 patient safety reports detailed injectable medication-related patient safety incidents: 59.7% (

conclusionInterventions to improve injectable end-of-life symptom control care should focus on ensuring timely access to assessments and prescriptions, enhancing continuity of care, and mechanisms to ensure rapid visits to administer medication.

Indexed as

InjectionsMedication ErrorsPatient SafetyTerminal CareEnglandHumansWalesdrug safetyend-of-life careinjectionspatient safetyprimary health caresubcutaneous

Identifiers

PMID41022519
PMCPMC13044229

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.