Evidence map›Paper›PMID 41022273›Full record

ArticleJournal of stroke and cerebrovascular diseases : the official journal of National Stroke Association2025

Precipitation, EMS use, and time to presentation of Acute Ischemic stroke in the get with the guidelines-stroke registry.

Marisa Berner, Mathew Reeves, George S Usmanov, Kevin N Sheth, Amar Dhand

Abstract read
In one paragraph

Article in Journal of stroke and cerebrovascular diseases : the official journal of National Stroke Association, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0citing papers in PubMed
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1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

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5 · Who and what money

Authors and funding

5 authors.

Marisa BernerHarvard Medical School, 25 Shattuck Street, Boston, MA 02115, USA; Department of Neurology, Brigham & Women's Hospital, 65 Landsdowne Street, Cambridge, MA 02139, USA.
Mathew ReevesDepartment of Epidemiology and Biostatistics, Michigan State University, 909 Wilson Road Room B601, East Lansing, MI 48824, USA.
George S UsmanovHarvard Medical School, 25 Shattuck Street, Boston, MA 02115, USA; Department of Neurology, Brigham & Women's Hospital, 65 Landsdowne Street, Cambridge, MA 02139, USA.
Kevin N ShethDepartment of Neurology & Neurosurgery, Yale School of Medicine, 800 Howard Avenue, New Haven, CT 06519, USA; Yale Center for Brain & Mind Health, 333 Cedar Street, New Haven, CT 06510, USA.
Amar DhandHarvard Medical School, 25 Shattuck Street, Boston, MA 02115, USA; Department of Neurology, Brigham & Women's Hospital, 65 Landsdowne Street, Cambridge, MA 02139, USA; Network Science Institute, Northeastern University, 177 Huntington Avenue, #1010, Boston, MA 02115, USA. Electronic address: adhand@bwh.harvard.edu.

Funding

Social networks and risk of delayed arrival to the hospital during strokeR01MD016178 · NIMHD · BRIGHAM AND WOMEN'S HOSPITAL · PI Amar Dhand, Kevin Navin Sheth · 2022 to 2026
$3.7M
NIMHD NIH HHS R01 MD016178
6 · The paper itself

Abstract

backgroundDelayed presentation to the hospital is a barrier for delivering acute stroke treatments. The effects of weather on delay are unstudied. We examined the relationship between precipitation and time to arrival nationwide.

methodsWe studied patients with acute ischemic stroke who presented at a Get With the Guidelines®-Stroke hospital from 2010-2019. The exposure variable was total daily precipitation on the day of presentation, obtained from the National Oceanic and Atmospheric Administration, and categorized as none (0 inches/day), mild (>0-1 inch/day), and major (>1 inch/day). The primary outcome was time to hospital arrival after stroke (in minutes). We conducted multivariate regression analysis, including analysis of interaction between precipitation level and EMS usage.

resultsIn ∼2.7 million patients, 50.7% were female and 38.6% were ≥75 years old. Median time to hospital arrival was 212 minutes in no precipitation, 219 minutes in mild precipitation, and 223 minutes in major precipitation. In adjusted analyses, compared to no precipitation, mild precipitation was associated with 4.63 minutes of delay [95% CI: (2.77, 6.49)]. Major precipitation was associated with 7.69 minutes of delay [95% CI: (2.86, 12.52)]. EMS usage improved arrival time overall, and there was an interaction with mild precipitation (-6.09 minutes [95% CI: (-9.79 to -2.39)]). However, there was no interaction with major precipitation (-2.72 minutes [95% CI: (-12.38 to 6.93)]).

conclusionPrecipitation was associated with delayed presentation to the hospital in acute stroke. Increased frequency of extreme weather calls for developing EMS strategies and infrastructure to support climate-ready stroke systems of care.

Indexed as

Emergency Medical ServicesIschemic StrokeRainTime-to-TreatmentWeatherAgedAged, 80 and overFemaleHumansMaleMiddle AgedRegistriesRetrospective StudiesRisk FactorsTime FactorsTreatment OutcomeEmergency medical servicesIschemic strokeRegistriesTime-to-TreatmentWeather

Identifiers

PMID41022273
PMCPMC12536867

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.