Evidence map›Paper›PMID 41022155›Full record

ArticleThe Journal of nutrition2025

Dairy Intake and Coronary Artery Calcification: The Coronary Artery Risk Development in Young Adults (CARDIA) Prospective Cohort Study.

Ethan J Cannon, David R Jacobs, Lyn M Steffen, Mark J Pletcher, James M Shikany, Philip Greenland, Felipe V Martignoni, Pamela J Schreiner, Michael Miedema

Abstract read
In one paragraph

Article in The Journal of nutrition, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

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0 citing papers in PubMed.

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4 · The record

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PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Ethan J CannonDivision of Epidemiology & Community Health, University of Minnesota School of Public Health, Minneapolis, MN, United States. Electronic address: Canno317@umn.edu.
David R JacobsDivision of Epidemiology & Community Health, University of Minnesota School of Public Health, Minneapolis, MN, United States.
Lyn M SteffenDivision of Epidemiology & Community Health, University of Minnesota School of Public Health, Minneapolis, MN, United States.
Mark J PletcherUniversity of California, San Francisco, CA, United States.
James M ShikanyUniversity of Alabama at Birmingham, Birmingham, AL, United States.
Philip GreenlandNorthwestern University, Chicago, IL, United States.
Felipe V MartignoniMinneapolis Heart Institute, Minneapolis, MN, United States.
Pamela J SchreinerDivision of Epidemiology & Community Health, University of Minnesota School of Public Health, Minneapolis, MN, United States.
Michael MiedemaMinneapolis Heart Institute, Minneapolis, MN, United States; Minneapolis Heart Institute Foundation, Minneapolis, MN, United States.

Funding

Cardiovascular Disease Epidemiology &Prevention TrngT32HL007779 · NHLBI · UNIVERSITY OF MINNESOTA TWIN CITIES · PI PAMELA L. Lutsey, JAMES S PANKOW · 1994 to 2026
$9.3M
CORONARY ARTERY RISK DEVELOPMENT IN YOUNG ADULTS (CARDIA) STUDY - COORDINATING CENTER (CC)75N92023D00002 · NHLBI · UNIVERSITY OF ALABAMA AT BIRMINGHAM · PI LI, JING · 2023 to 2025
$6.8M
CORONARY ARTERY RISK DEVELOPMENT IN YOUNG ADULTS (CARDIA) STUDY - OAKLAND FIELD CENTER75N92023D00003 · NHLBI · KAISER FOUNDATION RESEARCH INSTITUTE · PI BHATT, ANKEET S. · 2023 to 2025
$2.2M
CORONARY ARTERY RISK DEVELOPMENT IN YOUNG ADULTS (CARDIA) STUDY - BIRMINGHAM FIELD CENTER75N92023D00005 · NHLBI · UNIVERSITY OF ALABAMA AT BIRMINGHAM · PI LEWIS, CORA · 2023 to 2025
$2.2M
CORONARY ARTERY RISK DEVELOPMENT IN YOUNG ADULTS (CARDIA) STUDY - CHICAGO FIELD CENTERDIVERSITY SUPPLEMENT FOR MORGANN WEST75N92023D00004 · NHLBI · NORTHWESTERN UNIVERSITY · PI CARNETHON, MERCEDES · 2023 to 2025
$2.1M
CORONARY ARTERY RISK DEVELOPMENT IN YOUNG ADULTS (CARDIA) STUDY - UNIVERSITY OF MINNESOTA FIELD CENTER.75N92023D00006 · NHLBI · UNIVERSITY OF MINNESOTA · PI SCHREINER, PAMELA J · 2023 to 2025
$1.7M
CORONARY ARTERY DISEASE RISK DEVELOPMENT IN YOUNG ADULTS-N01HC95095-268095095N01HC095095 · HC · UNIVERSITY OF ALABAMA AT BIRMINGHAM · PI WILLIAMS, DALE · 1989 to 2006
$376k
STUDY CORONARY HEART DISEASE RISK IN YOUNG ADULTSN01HC048050 · HC · KAISER FOUNDATION RESEARCH INSTITUTE · PI SIDNEY, STEPHEN · 1985 to 2000
$102k
STUDY CORONARY HEART DISEASE RISK IN YOUNG ADULTSN01HC048048 · HC · UNIVERSITY OF MINNESOTA TWIN CITIES · PI SCHREINER, PAMELA J · 1985 to 2000
$53k
NHLBI NIH HHS 75N92023D00002NHLBI NIH HHS 75N92023D00003NHLBI NIH HHS 75N92023D00004NHLBI NIH HHS 75N92023D00005NHLBI NIH HHS 75N92023D00006NHLBI NIH HHS HHSN268201300027CNHLBI NIH HHS N01 HC048048NHLBI NIH HHS N01 HC048050NHLBI NIH HHS N01 HC095095NHLBI NIH HHS T32 HL007779
6 · The paper itself

Abstract

backgroundStudies on the association of dairy intake and coronary artery disease have been inconsistent. Little is known about the relationship between dairy consumption in young adulthood and coronary artery calcification (CAC), a marker of subclinical coronary atherosclerosis.

objectivesThis prospective cohort study assessed the association of dairy intake and the presence of CAC.

methodsWe followed 3110 participants of the coronary artery risk development in young adults (CARDIA) study for 25 y after enrollment during 1985-1986 (ages 18-30 y). Dairy intake (averaged over the year 0 and 7 examinations) was derived from the CARDIA diet history. CAC assessment occurred at years 15, 20, and 25. Cox proportional hazards regression was used to investigate the association of CAC and total, whole-fat, and low-fat dairy as well as other dairy subgroups.

resultsA total of 904 participants were observed to have CAC during follow-up. After covariate adjustment, higher intake of whole-fat dairy was inversely associated with risk of CAC [hazard ratio for the highest compared with the lowest quartile: 0.76 (95% confidence interval: 0.61, 0.96)]. Further adjustment for body mass index, which was slightly lower in those who consumed more dairy, attenuated these results (P for trend across quartiles: 0.13). Associations with CAC of total and low-fat dairy, as well as individual dairy products and fermented dairy, were not statistically significant.

conclusionsAmong young adults in the CARDIA study, whole-fat dairy was inversely associated with the future presence of CAC. These results do not support dietary guidelines that emphasize low-fat dairy intake for the prevention of coronary artery disease.

Indexed as

CalcinosisCoronary Artery DiseaseCoronary VesselsDairy ProductsDietVascular CalcificationAdolescentAdultCohort StudiesDietary FatsFemaleHumansMaleProportional Hazards ModelsProspective StudiesRisk FactorsDietary Fatsbuttercardiovascular diseasecheesecreamdairyepidemiologyhumanmilknutritionsaturated fat

Identifiers

PMID41022155
PMCPMC12558414

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.