Evidence map›Paper›PMID 41022069›Full record

ArticleThe Journal of international medical research2025

A direct association between suicide and reduced amygdala volume: A retrospective study.

Elif Emre, Sevler Yildiz, Ayse Rumeysa Yaman Baran, Gulhan Kilicarslan, Suna Aydin, Esra Piril Agirbas, Burcu Sirlier Emir, İbrahim Sahin, Suleyman Aydin

Abstract read
In one paragraph

Article in The Journal of international medical research, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Elif EmreDepartment of Anatomy, Faculty of Medicine, Fırat University, Turkiye.
Sevler YildizDepartment of Psychiatry, Elazığ Fethi Sekin City Hospital, Turkiye.
Ayse Rumeysa Yaman BaranDepartment of Psychiatry, Elazığ Fethi Sekin City Hospital, Turkiye.
Gulhan KilicarslanDepartment of Radiology, Elazığ Fethi Sekin City Hospital, Turkiye.
Suna AydinDepartment of Cardiovascular Surgery, Elazığ Fethi Sekin City Hospital, Turkiye.
Esra Piril AgirbasDepartment of Anesthesiology and Reanimation, Ankara City Hospital, Turkiye.
Burcu Sirlier EmirDepartment of Psychiatry, Elazığ Fethi Sekin City Hospital, Turkiye.
İbrahim SahinDepartment of Medical Biology, Faculty of Medicine, Erzincan Binali Yildirim University, Turkiye.
Suleyman AydinDepartment of Biochemistry, Faculty of Medicine, Fırat University, Turkiye.ORCID 0000-0001-6162-3250

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

ObjectiveThe neurological causes of suicide remain poorly understood. This study sought to ascertain whether there is a correlation between amygdala volume and suicidal behavior.MethodsThis case-control retrospective study included 193 participants-108 healthy controls and 85 individuals with a history of suicide attempts. Sagittal magnetic resonance imaging was conducted for each participant, and cross-sectional areas of the left and right amygdala were determined independently using freehand tracing. The total volume of the amygdala was determined by multiplying the thickness of the slices by the sum of the regions.ResultsPatients with a history of suicide attempts had significantly decreased amygdala volumes on both the right (

Indexed as

AmygdalaSuicideSuicide, AttemptedAdultCase-Control StudiesFemaleHumansMagnetic Resonance ImagingMaleMiddle AgedOrgan SizeRetrospective StudiesROC CurveYoung AdultAmygdala volumemagnetic resonance imagingneurobiological causessuicidal behaviorsuicide attempt

Identifiers

PMID41022069
PMCPMC12480822

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.