Evidence map›Paper›PMID 41022068›Full record

Observational studyThe Journal of international medical research2025

Effect of targeted multilevel sleep surgery on resistant hypertension in patients with severe obstructive sleep apnea.

Ahmed Bahgat, Mostafa Elwany, Claudio Vicini, Yassin Bahgat, Giuseppe Magliulo, Antonio Greco, Armando De Virgilio, Annalisa Pace, Mario Giuseppe Bellizzi, Enrica Croce and 8 more

Abstract readObservational StudyMulticenter Study
PubMed Full text at PMC Publisher
In one paragraph

Observational study in The Journal of international medical research, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

18 authors.

Ahmed BahgatDepartment of Otorhinolaryngology-Head & Neck Surgery, Alexandria University, Egypt.
Mostafa ElwanyDepartment of Cardiology & Angiology, Alexandria University, Egypt.
Claudio ViciniDepartment ENT & Audiology, University of Ferrara, Italy.
Yassin BahgatDepartment of Otorhinolaryngology-Head & Neck Surgery, Alexandria University, Egypt.
Giuseppe MagliuloDepartment of 'Organi di Senso,' University "Sapienza," Italy.
Antonio GrecoDepartment of 'Organi di Senso,' University "Sapienza," Italy.
Armando De VirgilioDepartment of 'Organi di Senso,' University "Sapienza," Italy.
Annalisa PaceDepartment of 'Organi di Senso,' University "Sapienza," Italy.
Mario Giuseppe BellizziDepartment of 'Organi di Senso,' University "Sapienza," Italy.
Enrica CroceDepartment of 'Organi di Senso,' University "Sapienza," Italy.
Lodovica GattiDepartment of 'Organi di Senso,' University "Sapienza," Italy.
Antonino ManiaciDepartment of Otolaryngology, Kore University, Italy.
Jerome R LechienDepartment of Anatomy and Experimental Oncology, Mons School of Medicine, University of Mons, Belgium.
Alberto CarantiDepartment ENT & Audiology, University of Ferrara, Italy.
Stéphane GargulaENT-HNS Department, Aix Marseille Univ, APHM, CNRS, IUSTI, La Conception University Hospital, France.
Luigi A VairaMaxillofacial Surgery Operative Unit, Department of Medical, Surgical and Experimental Sciences, University of Sassari, Italy.
Heloisa Dos SantosDepartment of Otorhinolaryngology, Nucleus of Otolaryngology, Head and Neck Surgery and Sleep Medicine of São Paulo, Brazil.ORCID 0000-0002-0797-6810
Giannicola IannellaDepartment of 'Organi di Senso,' University "Sapienza," Italy.ORCID 0000-0003-1781-2809

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

ObjectiveObstructive sleep apnea is an independent risk factor for cardiovascular diseases, particularly resistant hypertension. For patients who are noncompliant or unable to tolerate continuous positive airway pressure therapy, surgical treatment may serve as a viable alternative. In this study, we evaluated the impact of multilevel sleep surgery on blood pressure levels in patients with resistant hypertension.MethodsThis is a bicentric retrospective observational study of 50 patients with severe obstructive sleep apnea and resistant hypertension who underwent multilevel targeted sleep surgery.ResultsClinical improvement was objectively confirmed by polygraphy performed 6 months after surgery, demonstrating a significant reduction in the mean Apnea-Hypopnea Index from 44.98 ± 14.94 to 22.16 ± 7.30 (

Indexed as

HypertensionSleep Apnea, ObstructiveAdultAgedAntihypertensive AgentsBlood PressureContinuous Positive Airway PressureFemaleHumansMaleMiddle AgedPolysomnographyRetrospective StudiesSleepTreatment OutcomeAntihypertensive AgentshypertensionObstructive sleep apneaobstructive sleep apnea comorbiditiesobstructive sleep apnea treatmentsleep surgery

Identifiers

PMID41022068
PMCPMC12480788

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.