Observational studyThe Journal of international medical research2025
Prechemoradiotherapy number of natural teeth as a prognostic factor in patients with locally advanced nasopharyngeal cancer: A retrospective observational study.
Observational study in The Journal of international medical research, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
ObjectiveThis study evaluated the prognostic value of the pretreatment number of natural teeth on progression-free survival and overall survival in patients with locally advanced nasopharyngeal carcinoma treated with concurrent chemoradiotherapy.MethodsWe retrospectively analyzed 248 patients with locally advanced nasopharyngeal carcinoma treated with intensity-modulated radiotherapy-based concurrent chemoradiotherapy and adjuvant chemotherapy between June 2010 and December 2021. The number of natural teeth was assessed before concurrent chemoradiotherapy. A receiver operating characteristic curve analysis was performed to identify the optimal number of natural teeth threshold predictive of overall survival and progression-free survival.ResultsThe optimal cutoff value for the number of natural teeth was 19.5 (area under the curve: 70.6%). Patients were grouped into those with a number of natural teeth <20 (
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