ArticleAmerican journal of physiology. Regulatory, integrative and comparative physiology2025
Longitudinal changes in cardiovascular and sympathetic neural responses to static handgrip exercise throughout pregnancy.
Article in American journal of physiology. Regulatory, integrative and comparative physiology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
The time-course changes in the exercise pressor response throughout gestation remain unknown. As pregnancy is associated with altered hemodynamics and sympathetic activation, we hypothesized that neural responses to static handgrip (SHG) exercise would be augmented, especially during late pregnancy. Forty-six women (30 ± 6 yr [SD]) were studied longitudinally during early and late pregnancy and postpartum. Mean arterial pressure (MAP), cardiac output (Qc), total peripheral resistance (TPR = MAP/Qc), and muscle sympathetic nerve activity (MSNA) were measured during supine rest and SHG at 40% of maximal voluntary contraction force until fatigue, followed by 2-min postexercise circulatory occlusion (PECO) to isolate muscle metaboreflex activation. The peak increase (Δ) in MAP during fatiguing SHG did not differ among gestation stages (
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