Evidence map›Paper›PMID 41021477›Full record

ArticlePsychology and aging2026

Occupational social interaction is associated with reduced dementia risk: The Trøndelag Health Study (HUNT).

Bernt Bratsberg, Jennifer R Harris, Vegard Skirbekk, Yaakov Stern, Asta Kristine Håberg, Geir Selbæk, Bjørn Heine Strand, Trine Holt Edwin

Abstract read
In one paragraph

Article in Psychology and aging, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Bernt BratsbergRagnar Frisch Center for Economic Research.
Jennifer R HarrisCentre for Fertility and Health, Norwegian Institute of Public Health.
Vegard SkirbekkCentre for Fertility and Health, Norwegian Institute of Public Health.
Yaakov SternDepartment of Neurology, Cognitive Neuroscience Division, Columbia University, Vagelos College of Physicians and Surgeons.
Asta Kristine HåbergDepartment for Physical Health and Aging, Norwegian Institute of Public Health.
Geir SelbækNorwegian National Centre for Ageing and Health, Vestfold Hospital Trust.
Bjørn Heine StrandDepartment for Physical Health and Aging, Norwegian Institute of Public Health.
Trine Holt EdwinDepartment of Geriatric Medicine, Oslo University Hospital.ORCID 0000-0002-0530-8771

Funding

Changing lives, changing brains: How modern family and work life influences ADRD risksR01AG069109 · NIA · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI STERN, YAAKOV · 2020 to 2025
$3.1M
European Research CouncilNIA NIH HHS R01 AG069109NIH HHSNorwegian Research CouncilResearch Council of Norway
6 · The paper itself

Abstract

Lifetime social engagement could build cognitive reserve and lower the risk of dementia through compensatory effects on brain health. We aimed to investigate whether social interaction at work is protective of later-life cognitive impairment. Data from 9,248 participants of the population-based Norwegian HUNT4 70+ Study (2017-2019), with cognitive assessments at or after age 70, were linked retrospectively to longitudinal registry-based employment information spanning ages 30-65 years. An occupational social interaction score was computed using occupational characteristics from the O*NET database. Multinomial logistic regression was used to estimate the associations between occupational social interaction and dementia and mild cognitive impairment (MCI), while linear regression was used to model the association with cognition using the Montreal Cognitive Assessment (MoCA). The models were subsequently adjusted for confounding variables age, sex, education, and apolipoprotein E-ε4 genotype, as well as for midlife family, health, and lifestyle-related variables collected from national registries and earlier Trøndelag Health Study waves. Higher occupational social interaction was associated with reduced risks of dementia and MCI, and better MoCA performance. Adjusted for confounding from age, sex, education, and apolipoprotein E-ε4, each standard deviation higher occupational social interaction score was associated with a relative risk ratio of 0.89 for dementia (

Indexed as

Cognitive DysfunctionDementiaEmploymentOccupationsSocial InteractionAdultAgedFemaleHumansLongitudinal StudiesMaleMiddle AgedNorwayRetrospective StudiesRisk Factors

Identifiers

PMID41021477
PMCPMC12670332

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.