Evidence map›Paper›PMID 41021297›Full record

ArticleEuropean journal of public health2025

Prospective associations between diabetes and depressive symptoms across European regions: a secondary analysis of ELSA, TILDA, and SHARE datasets.

Jaroslav Gottfried, Katarzyna Gajewska, Belinda Hernández, Rose Anne Kenny, Cathy Lloyd, Arie Nouwen, Shane O'Donnell, Ricardo Rodrigues, Norbert Schmitz, Sonya Deschênes

Abstract read
In one paragraph

Article in European journal of public health, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Jaroslav GottfriedSchool of Psychology, University College Dublin, Dublin, Ireland.ORCID 0000-0002-6076-1632
Katarzyna GajewskaDiabetes Ireland, Dublin, Ireland.ORCID 0000-0002-7536-0591
Belinda HernándezNational Centre for Pharmacoeconomics, Dublin, Ireland.ORCID 0000-0001-5034-1282
Rose Anne KennyThe Irish Longitudinal Study on Ageing, Trinity College Dublin, Dublin, Ireland.ORCID 0000-0002-9336-8124
Cathy LloydFaculty of Wellbeing, Education & Language Studies, The Open University, Milton Keynes, United Kingdom.ORCID 0000-0002-8863-3069
Arie NouwenDepartment of Psychology, Middlesex University, London, United Kingdom.ORCID 0000-0002-0609-4082
Shane O'DonnellSchool of Business, University College Dublin, Dublin, Ireland.ORCID 0000-0002-3778-705X
Ricardo RodriguesSOCIUS/CSG, ISEG (Lisbon School of Economics & Management), University of Lisbon, Lisbon, Portugal.ORCID 0000-0001-8438-4184
Norbert SchmitzPopulation-Based Medicine, University of Tübingen, Tübingen, Germany.ORCID 0000-0001-7777-6323
Sonya DeschênesSchool of Psychology, University College Dublin, Dublin, Ireland.ORCID 0000-0002-9258-0895

Funding

German Ministry of Education and Research, the Max Planck Society for the Advancement of Science, the U.S. National Institute on Aging U01_AG09740-13S2, P01_AG005842, P01_AG08291, P30_AG12815, R21_AG025169, Y1-AG-4553-01, IAG_BSR06-11, OGHA_04-064, BSR12-04, R01_AG052527-02, HHSN271201300071C, RAG052527AHealth Research Board SDAP-2023-001Ireland Department of Health, the Atlantic Philanthropies, the Ireland Health Research Board (HSB), the Irish Life, and the Science Foundation IrelandNational Institute On Aging of the National Institutes of Health R01AG017644NIHR Policy Research Programme (HEI) 198_1074_03
6 · The paper itself

Abstract

This article investigates predictive associations between diabetes and depressive symptoms across Ireland, the United Kingdom, and four European regions. The data were obtained by merging datasets from three large prospective cohort studies-the English Longitudinal Study on Ageing, The Irish Longitudinal study on Ageing, and the Survey on Health, Ageing and Retirement in Europe. We first applied a survival analysis design to two samples of 43 061 and 35 993 participants, investigating elevated depressive symptoms as a risk factor for diabetes, and diabetes as a risk factor for elevated depressive symptoms, respectively. We next applied a multilevel modeling approach to examine depressive symptoms before, during, and after diabetes onset across 101 799 participants. We found a bidirectional association between diabetes and depressive symptoms; however, the strength of these associations did not significantly differ between the regions (P > .01). The results also showed that individuals with newly diagnosed diabetes consistently reported higher depressive symptoms than those without diabetes, even before diagnosis. However, we observed no country-specific differences in the gradual changes in depressive symptoms regardless of participants' diabetes status. Diabetes at baseline was associated with higher risk of developing depression; and vice versa. These associations were not moderated by geographical location. Therefore, the risks of diabetes and depressive symptoms comorbidity seem to be equal across all observed geographic regions.

Indexed as

DepressionDiabetes MellitusAgedComorbidityEuropeFemaleHumansIrelandLongitudinal StudiesMaleMiddle AgedProspective StudiesRisk Factors

Identifiers

PMID41021297
PMCPMC12707472

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.