ArticleJournal of cancer survivorship : research and practice2025
The long shadow of family-internal and -external adverse childhood experiences: associations with mental functioning in middle-aged and older cancer survivors.
Article in Journal of cancer survivorship : research and practice, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
1 citing paper in PubMed, 1 synthesis or guideline pooled it.
- Efficacy of technology-based psychosocial interventions on quality of life and psychological outcomes in adolescent and young adult survivors of childhood cancer: a systematic review and meta-analysis of randomized controlled trials.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2026Pooled it
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors.
Funding
Abstract
objectiveMiddle-aged and older cancer survivors, who face both age-related and cancer-related stressors, are particularly vulnerable in terms of mental functioning. From a life-course perspective, this study investigates the long-term associations between family-internal adverse childhood experiences (ACEs)-specifically childhood parental mental distress-and family-external ACEs-childhood peer bullying and friendship-and mental functioning in this population.
methodsData were drawn from 419 cancer survivors (mean age = 63.41, SD = 9.64) and 8209 non-cancer respondents (mean age = 59.64, SD = 8.67) from the 2014 and 2020 waves of the China Health and Retirement Longitudinal Study, a nationally representative survey employing a stratified multi-stage cluster sampling design. Structural equation modeling was used to test the hypotheses, following STROBE reporting guidelines.
resultsChildhood parental mental distress was significantly and negatively associated with mental functioning in cancer survivors, with childhood peer friendship and bullying mediating this relationship. Among the mediators, the association between peer friendship and mental functioning was stronger than that between peer bullying and mental functioning. Furthermore, these associations were more pronounced in cancer survivors than in non-cancer respondents.
conclusionsBoth family-internal and -external ACEs are significantly associated with lower levels of mental functioning in cancer survivors, with family-external ACEs serving as mediators. IMPLICATIONS FOR CANCER SURVIVORS: Given that the mental functioning of middle-aged and older cancer survivors is undermined by the combined effects of ACEs-related, age-related, and cancer-related stressors, intervention strategies should adopt an integrative life-course perspective that concurrently addresses all three domains to effectively protect their mental functioning.
Indexed as
Identifiers
41021208What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.