Assessment of myocardial viability using cardiac magnetic resonance feature tracking at rest and during low-dose dobutamine stress: a comparison with delayed gadolinium enhancement.

Nisreen A A Mohammed, Abdulrahman Hamdan, Gehan S Seifeldein, Soha Romeih, Mahmoud Shaaban, Wesam Elmozy

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Article in The international journal of cardiovascular imaging, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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6 authors.

Nisreen A A MohammedRadiology Department, Faculty of Medicine, Assiut University, Assiut, Egypt.

Abdulrahman HamdanRadiology Department, Faculty of Medicine, Assiut University, Assiut, Egypt. abdulrahman.emam@med.aun.edu.eg.

Gehan S SeifeldeinRadiology Department, Faculty of Medicine, Assiut University, Assiut, Egypt.

Soha RomeihAswan Heart Centre (Magdi Yacoub Foundation), Aswan, Egypt.

Mahmoud ShaabanAswan Heart Centre (Magdi Yacoub Foundation), Aswan, Egypt.

Wesam ElmozyAswan Heart Centre (Magdi Yacoub Foundation), Aswan, Egypt.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundAccurate assessment of myocardial viability is crucial for guiding treatment decisions in patients with ischemic cardiomyopathy (ICM). Delayed gadolinium enhancement (DGE) is the current gold standard, but non-contrast methods like feature tracking (FT) analysis during dobutamine stress are emerging. This work evaluates the efficiency of myocardial viability assessment using cardiac magnetic resonance feature tracking (CMR-FT) during stress by low-dose dobutamine.

methodsThis retrospective case-control study enrolled 50 ICM patients who underwent CMR at rest and during low-dose dobutamine stress. FT analysis was performed to assess circumferential, radial, and longitudinal strain at both rest and stress. DGE was used as reference to determine viability.

resultsSignificant strain improvement with dobutamine was observed in segments deemed viable by DGE, while non-viable segments showed no improvement.

conclusionCMR-FT during low-dose dobutamine stress shows promise as non-contrast method for assessing myocardial viability in ICM patients, providing a potential alternative to DGE.

Indexed as

CardiomyopathiesContrast MediaDobutamineGadolinium DTPAMagnetic Resonance Imaging, CineMyocardial ContractionMyocardial IschemiaMyocardiumOrganometallic CompoundsVentricular Function, LeftAgedCase-Control StudiesFemaleHumansMaleMiddle AgedContrast MediaDobutamineGadolinium DTPAOrganometallic CompoundsCardiac magnetic resonance (CMR)Delayed gadolinium enhancement (DGE)Dobutamine stressFeature tracking (FT)IschemiccardiomyopathyMyocardial viabilityStrainanalysis

Identifiers

PMID41021171

DOI10.1007/s10554-025-03514-7

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