ArticleTropical animal health and production2025
Trehalose improves growth performance and gut health of yellow-feathered broilers exposed to heat stress.
Article in Tropical animal health and production, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
This study investigated the efficacy of dietary trehalose supplementation in mitigating the adverse effects of heat stress (HS) on yellow-feathered broilers, with a focus on growth performance, serum biochemical profiles, and gut microbiota. A total of 240 day-old broilers were randomly assigned to four groups (six replicates per group): the control group (24 ± 2 °C plus basal diet), the HS0 (33 ± 2 °C plus basal diet), the HS0.1 (33 ± 2 °C plus basal diet supplemented with 0.1% trehalose), and the HS0.5 (33 ± 2 °C plus basal diet supplemented with 0.5% trehalose). Body weight of broilers at 56 days of age (DOA) were significantly decreased by heat stress (P = 0.00). Birds in the HS0.5 group exhibited higher body weight at 28 DOA compared to those in the HS0 and HS0.1 groups. Serum analysis revealed that heat stress decreased total antioxidant capacity (T-AOC) and increased malondialdehyde (MDA) content (P < 0.05), effects that were reversed by trehalose supplementation. Heat stress increased the concentration of alanine aminotransferase (ALT) at 56 DOA, which was mitigated by trehalose supplementation (P = 0.00). Neither heat stress nor trehalose supplementation affected immune organ indices or meat quality parameters (P > 0.05). In terms of gut microbiota, compared with the control group, heat stress significantly increased the relative abundance of Halobacterota and decreased the abundance of Alistipes (P ≤ 0.05). LEfSe analysis identified more enriched microbial biomarkers Bacteroides barnesiae, Deferribacteres and Rikenellaceae_RC9_gut_group in the HS0.5 group than in other groups. Overall, trehalose supplementation demonstrated potential to improve performance and gut health of heat-stressed broilers through enhanced antioxidant capacity and gut microbiota modulation, warranting further studies to optimize the supplementation amount.
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