ReviewAbdominal radiology (New York)2026
Gallbladder neuroendocrine neoplasms: a review.
Review in Abdominal radiology (New York), 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
3 citing papers in PubMed.
- Case report: A challenging case of stage IVB mixed neuroendocrine-non-neuroendocrine neoplasm of the gallbladder treated with extended radical resection including portal vein reconstruction.Frontiers in oncology · 2026Article
- Incidental Detection of a Well-Differentiated Neuroendocrine Tumor of the Gallbladder: A Case Report.Cureus · 2026Article
- Clinicopathological characteristics and treatment outcomes of biliary neuroendocrine carcinoma: a single-center case series and literature review.Frontiers in oncology · 2026Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Gallbladder neuroendocrine neoplasms (GB-NENs) are rare, aggressive tumors that represent a unique subset of biliary tract malignancies. The etiology remains poorly understood, with hypotheses suggesting origins from metaplasia induced by chronic inflammation or differentiation from adenocarcinoma. Most GB-NENs present with vague or absent symptoms, leading to frequent incidental detection during cholecystectomy or at advanced stages with distant metastases. Diagnosis is challenging due to the lack of specific clinical and imaging features; thus, histopathological evaluation with immunohistochemical staining for neuroendocrine markers is necessary. Treatment is not standardized; it typically follows strategies for gallbladder adenocarcinoma and other neuroendocrine neoplasms. Surgical resection is the mainstay for localized disease and has the greatest impact on survival. This review provides an updated synthesis of the epidemiology, pathogenesis, clinicopathological features, diagnostic criteria, and evolving management of GB-NENs, highlighting ongoing research in this challenging but increasingly recognized disease entity.
Indexed as
Identifiers
41021016What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.