ArticleGraefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie2025
The relationship between morphological and functional status and ocular blood flow in retinitis pigmentosa assessed by laser speckle flowgraphy.
Article in Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purposesTo evaluate the mean blur rate-choroid (MBR-CH) and the optic nerve head (ONH) by laser speckle flowgraphy (LSFG) in patients with retinitis pigmentosa (RP) compared with those of healthy controls and to determine whether the MBR-CH is associated with chorio-retinal structure and visual function. SUBJECTS AND
methodsWe studied 48 eyes of 24 RP patients and 71 controls, evaluating the MBR in the ONH (MBR-Tissue, -Vessel, and -All), MBR-CH, and the area ratio of the bloodstream (ARBS). We identified the central foveal thickness, subfoveal choroidal thickness (SCT), ellipsoid zone (EZ) width, retinal sensitivity by microperimetry, and Goldmann visual field (GVF) of I4e and I2e intensities.
resultsAll LSFG parameters in the RP group were significantly lower than those of the controls. The SCT was significantly correlated with axial length, visual acuity (VA), retinal sensitivity at 2°, MBR-CH, and ARBS. The EZ width was significantly correlated with retinal sensitivity, MBR-Tissue, and CH. VA and MBR-Vessel were identified as factors independently contributing to the retinal sensitivity at 2°; the EZ width and MBR-Vessel independently contributed to the retinal sensitivity at 10°. The EZ width, MBR-Vessel, and ARBS independently contributed to the GVF I4e area, and EZ width and MBR-Vessel independently contributed to the GVF I2e area.
conclusionThe LSFG-measured ONH and CH blood flow are important indicators for understanding the chorio-retinal structure and visual function in RP.
Indexed as
Identifiers
41020974What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.