Evidence map›Paper›PMID 41020929›Full record

ArticleArchives of toxicology2026

Prioritizing alternative halogenated flame retardants in mangrove spiders: high maternal transfer toxicity outweighs low environmental burden.

Qiang Xie, Lvyan Tan, Congmo Jin, Wei Wei, Fenglong Jia, Yuping Wu, Haoyu Jiang, Shichun Zou, Baowei Chen, Tiangang Luan and 2 more

Abstract read
PubMed Publisher
In one paragraph

Article in Archives of toxicology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Qiang XieSchool of Life Sciences, State Key Laboratory of Biocontrol, Sun Yat-Sen University, Guangzhou, 510275, China.ORCID 0000-0001-5630-5223
Lvyan TanSchool of Life Sciences, State Key Laboratory of Biocontrol, Sun Yat-Sen University, Guangzhou, 510275, China.
Congmo JinSouth China Sea Bio-Resource Exploitation and Utilization Collaborative Innovation Center, Guangdong Provincial Key Laboratory of Marine Resources and Coastal Engineering, School of Marine Sciences, Sun Yat-Sen University, Zhuhai, 519082, China.
Wei WeiSchool of Life Sciences, State Key Laboratory of Biocontrol, Sun Yat-Sen University, Guangzhou, 510275, China.
Fenglong JiaSchool of Life Sciences, State Key Laboratory of Biocontrol, Sun Yat-Sen University, Guangzhou, 510275, China.
Yuping WuSouth China Sea Bio-Resource Exploitation and Utilization Collaborative Innovation Center, Guangdong Provincial Key Laboratory of Marine Resources and Coastal Engineering, School of Marine Sciences, Sun Yat-Sen University, Zhuhai, 519082, China.
Haoyu JiangSouth China Sea Bio-Resource Exploitation and Utilization Collaborative Innovation Center, Guangdong Provincial Key Laboratory of Marine Resources and Coastal Engineering, School of Marine Sciences, Sun Yat-Sen University, Zhuhai, 519082, China.
Shichun ZouSouth China Sea Bio-Resource Exploitation and Utilization Collaborative Innovation Center, Guangdong Provincial Key Laboratory of Marine Resources and Coastal Engineering, School of Marine Sciences, Sun Yat-Sen University, Zhuhai, 519082, China.
Baowei ChenSouth China Sea Bio-Resource Exploitation and Utilization Collaborative Innovation Center, Guangdong Provincial Key Laboratory of Marine Resources and Coastal Engineering, School of Marine Sciences, Sun Yat-Sen University, Zhuhai, 519082, China.
Tiangang LuanSchool of Life Sciences, State Key Laboratory of Biocontrol, Sun Yat-Sen University, Guangzhou, 510275, China.
Lihua YangSouth China Sea Bio-Resource Exploitation and Utilization Collaborative Innovation Center, Guangdong Provincial Key Laboratory of Marine Resources and Coastal Engineering, School of Marine Sciences, Sun Yat-Sen University, Zhuhai, 519082, China. yanglih2@mail.sysu.edu.cn.
Li LinSchool of Life Sciences, State Key Laboratory of Biocontrol, Sun Yat-Sen University, Guangzhou, 510275, China. linl@mail.sysu.edu.cn.

Funding

China Postdoctoral Science Foundation 2023M744088China Postdoctoral Science Foundation 2025T180753Fundamental Research Funds for the Central Universities, Sun Yat-sen University 24qnpy071Guangdong Basic and Applied Basic Research Foundation 2023A1515110328Key-Area Research and Development Program of Guangdong Province 2020B1111350003National Natural Science Foundation of China 22127810National Natural Science Foundation of China 22176224
6 · The paper itself

Abstract

Halogenated organic contaminants (HOCs) pose significant ecological risks to mangrove spiders through bioaccumulation via food webs and maternal transfer to spiderlings. However, it remains unclear which specific HOCs pose the most critical intergenerational threats to spider populations. A study of 107 HOCs in spiders (Nephila pilipes) and their prey within South China mangroves revealed that accumulation varied by habitat (Shenzhen > Zhuhai) and life stage (reduced levels in gravid cephalothoraxes). Bio-magnification factors (BMF) exceeded unity for several HOCs, particularly short- and medium-chain chlorinated paraffins (SCCPs/MCCPs; ~ 2.7). Maternal transfer ratios (MTR) ranged from 0.43 to 0.94, peaked for dichlorodiphenyltrichloroethanes (DDTs, 0.74) and exhibited parabolic trends with carbon chain length (peak at C14) and chlorination degree (peak at Cl8). Although alternative halogenated flame retardants (AHFRs) constituted only 0.72% of total HOCs, they displayed the highest hazard quotients (HQ = 7.53) and the maternal transfer toxicity indices (MTTI = 5.35; MTTI/HQ ratio = 0.70), indicating substantial intergenerational risks. The increasing prevalence of AHFRs among regional fauna, combined with their metabolic persistence, highlights an urgent need to incorporate these compounds into environmental monitoring and regulatory frameworks. The newly proposed MTTI framework provides a quantitative basis for prioritizing both legacy and emerging HOCs, thereby guiding congener-specific eco-toxicological research and targeted management strategies aimed at preserving coastal predator-prey dynamics under escalating chemical stress.

Indexed as

Flame RetardantsHydrocarbons, HalogenatedSpidersAnimalsChinaEnvironmental MonitoringFemaleFood ChainWetlandsFlame RetardantsHydrocarbons, HalogenatedBio-magnificationHalogenated organic contaminantsMaternal transfer toxicity indicesNephila pilipes

Identifiers

PMID41020929

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.