Evidence map›Paper›PMID 41020868›Full record

ArticleCurrent issues in molecular biology2025

Serum TNF -α, IL-10 and IL-2 Trajectories and Outcomes in NSCLC and Melanoma Under Anti-PD-1 Therapy: Longitudinal Real-World Evidence from a Single Center.

Alina Miruna Grecea-Balaj, Olga Soritau, Ioana Brie, Maria Perde-Schrepler, Piroska Virag, Eva Fischer-Fodor, Nicolae Todor, Mihai Cenariu, Ioana Nedelea, Tudor Eliade Ciuleanu

Abstract read
In one paragraph

Article in Current issues in molecular biology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Review
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Alina Miruna Grecea-BalajDepartment of Medical Oncology, Oncology Institute "Prof. Dr. Ion Chiricuta", 400015 Cluj-Napoca, Romania.ORCID 0000-0002-3868-532X
Olga SoritauDepartment of Tumor Biology and Radiobiology, Oncology Institute "Prof. Dr. Ion Chiricuta", 400015 Cluj-Napoca, Romania.ORCID 0000-0002-9270-8529
Ioana BrieDepartment of Tumor Biology and Radiobiology, Oncology Institute "Prof. Dr. Ion Chiricuta", 400015 Cluj-Napoca, Romania.
Maria Perde-SchreplerDepartment of Tumor Biology and Radiobiology, Oncology Institute "Prof. Dr. Ion Chiricuta", 400015 Cluj-Napoca, Romania.ORCID 0000-0001-8581-0982
Piroska ViragDepartment of Tumor Biology and Radiobiology, Oncology Institute "Prof. Dr. Ion Chiricuta", 400015 Cluj-Napoca, Romania.
Eva Fischer-FodorDepartment of Tumor Biology and Radiobiology, Oncology Institute "Prof. Dr. Ion Chiricuta", 400015 Cluj-Napoca, Romania.ORCID 0000-0002-0898-0547
Nicolae TodorDepartment of Biostatistics, Oncology Institute "Prof. Dr. Ion Chiricuta", 400015 Cluj-Napoca, Romania.ORCID 0000-0002-8526-1263
Mihai CenariuDepartment of Animal Reproduction, University of Agricultural Sciences and Veterinary Medicine, 400372 Cluj-Napoca, Romania.ORCID 0000-0001-6501-0128
Ioana NedeleaDepartment of Medical Oncology, Emergency County Hospital "Dr. Constantin Opris", 430031 Baia Mare, Romania.
Tudor Eliade CiuleanuDepartment of Medical Oncology, Oncology Institute "Prof. Dr. Ion Chiricuta", 400015 Cluj-Napoca, Romania.ORCID 0000-0003-0958-5597

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

This prospective single-center study examined associations between serum cytokines-TNF-α, IL-2, and IL-10-and outcomes in stage IV non-small cell lung cancer (NSCLC,

Indexed as

cytokinesIL-10Il-2immune checkpoint inhibitormelanomaNSCLCTNF-α

Identifiers

PMID41020868
PMCPMC12468888

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.