Evidence map›Paper›PMID 41020815›Full record

ArticleCurrent issues in molecular biology2025

The

Zhenxing Wang, Xia Li, Shiyi Zhang, Jiamin Sun, Qinchen Lu, Yuting Tao, Shuang Liang, Xiuwan Lan, Jianhong Zhong, Qiuyan Wang

Abstract read
In one paragraph

Article in Current issues in molecular biology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Zhenxing WangGuangxi Key Laboratory for Genomic and Personalized Medicine, Guangxi Medical University, Nanning 530021, China.
Xia LiGuangxi Key Laboratory for Genomic and Personalized Medicine, Guangxi Medical University, Nanning 530021, China.
Shiyi ZhangGuangxi Key Laboratory for Genomic and Personalized Medicine, Guangxi Medical University, Nanning 530021, China.
Jiamin SunGuangxi Key Laboratory for Genomic and Personalized Medicine, Guangxi Medical University, Nanning 530021, China.
Qinchen LuGuangxi Key Laboratory for Genomic and Personalized Medicine, Guangxi Medical University, Nanning 530021, China.ORCID 0000-0002-5408-2377
Yuting TaoGuangxi Key Laboratory for Genomic and Personalized Medicine, Guangxi Medical University, Nanning 530021, China.
Shuang LiangGuangxi Key Laboratory for Genomic and Personalized Medicine, Guangxi Medical University, Nanning 530021, China.
Xiuwan LanDepartment of Biochemistry and Molecular Biology, School of Basic Medical Sciences, Guangxi Medical University, Nanning 530021, China.
Jianhong ZhongDepartment of Hepatobiliary Surgery, Guangxi Medical University Cancer Hospital, Nanning 530021, China.ORCID 0000-0002-1494-6396
Qiuyan WangGuangxi Key Laboratory for Genomic and Personalized Medicine, Guangxi Medical University, Nanning 530021, China.

Funding

Guangxi Natural Science Fund for Innovation Research Team 2016GXNSFGA380006Guangxi science and technology development project 2024GXNSFAA010070Guangxi science and technology development project AB23026002Guangxi science and technology development project AD22035042Innovation Project of Guangxi Graduate Education YCBZ2023101Natural Science Foundation of China 82260569
6 · The paper itself

Abstract

Hepatocellular carcinoma (HCC) is a malignancy that is notorious for its dismal prognosis. Dysregulation of the tumor microenvironment (TME) in HCC has emerged as a key hallmark in determining disease progression and the response to immunotherapy. The aim of this study was to identify novel TME regulators that contribute to therapeutic resistance, thus providing mechanistic insights for targeted interventions. The expression of

Indexed as

COX-2HCCimmunosuppressive microenvironmentimmunotherapySMIM25

Identifiers

PMID41020815
PMCPMC12468620

What OpenQuestion holds

Textmetadata
LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.