Evidence map›Paper›PMID 41020608›Full record

ArticlemBio2025

Samuel Rodrigues Dos Santos Junior, Piotr R Stempinski, Marcelo Valdemir de Araujo, Kevin Rojas, Gracen R Gerbig, Livia C Liporagi Lopes, Daniel F Q Smith, Maggie P Wear, Arturo Casadevall

Abstract read
In one paragraph

Article in mBio, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

  1. Review
  2. Article
  3. Article
  4. Article
  5. Review
  6. Molecular Architecture ofbioRxiv : the preprint server for biology · 2026
    Article
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Samuel Rodrigues Dos Santos JuniorW. Harry Feinstone Department of Molecular Microbiology and Immunology, The Johns Hopkins Bloomberg School of Public Health, Baltimore, Maryland, USA.ORCID 0000-0001-5564-3538
Piotr R StempinskiW. Harry Feinstone Department of Molecular Microbiology and Immunology, The Johns Hopkins Bloomberg School of Public Health, Baltimore, Maryland, USA.
Marcelo Valdemir de AraujoDepartamento de Imunologia, Universidade de São Paulo, Instituto de Ciências Biomédicas, São Paulo, Brazil.
Kevin RojasW. Harry Feinstone Department of Molecular Microbiology and Immunology, The Johns Hopkins Bloomberg School of Public Health, Baltimore, Maryland, USA.
Gracen R GerbigW. Harry Feinstone Department of Molecular Microbiology and Immunology, The Johns Hopkins Bloomberg School of Public Health, Baltimore, Maryland, USA.
Livia C Liporagi LopesW. Harry Feinstone Department of Molecular Microbiology and Immunology, The Johns Hopkins Bloomberg School of Public Health, Baltimore, Maryland, USA.
Daniel F Q SmithW. Harry Feinstone Department of Molecular Microbiology and Immunology, The Johns Hopkins Bloomberg School of Public Health, Baltimore, Maryland, USA.ORCID 0000-0002-7674-9988
Maggie P WearW. Harry Feinstone Department of Molecular Microbiology and Immunology, The Johns Hopkins Bloomberg School of Public Health, Baltimore, Maryland, USA.
Arturo CasadevallW. Harry Feinstone Department of Molecular Microbiology and Immunology, The Johns Hopkins Bloomberg School of Public Health, Baltimore, Maryland, USA.ORCID 0000-0002-9402-9167

Funding

Translational Research Central ServicesP30CA006973 · NCI · JOHNS HOPKINS UNIVERSITY · PI ALAN KEITH MEEKER · 1985 to 2026
$208.6M
Vaccine Response and Immunotherapeutics SWGP30AI094189 · NIAID · JOHNS HOPKINS UNIVERSITY · PI Anna Palmer Durbin · 2012 to 2026
$67.0M
Biology of Fungal MelaninR01AI052733 · NIAID · YESHIVA UNIVERSITY · PI CASADEVALL, ARTURO · 2003 to 2019
$6.6M
Conjugate vaccines for prevention and treatment of cryptococcosis - COVID-19 Revision SupplementR01AI152078 · NIAID · JOHNS HOPKINS UNIVERSITY · PI CASADEVALL, ARTURO · 2020 to 2024
$5.1M
Exploiting antibody catalysis for treating CryptococcosisR01AI162381 · NIAID · JOHNS HOPKINS UNIVERSITY · PI CASADEVALL, ARTURO · 2021 to 2025
$3.7M
Fundação de Amparo à Pesquisa do Estado de São Paulo 2023/00532-4National Institutes of Health - National Institute of Allergy and Infectious Diseases R01AI162381, R01AI152078, R01AI052733NCI NIH HHS P30 CA006973NIAID NIH HHS P30 AI094189NIAID NIH HHS R01 AI052733NIAID NIH HHS R01 AI152078NIAID NIH HHS R01 AI162381
6 · The paper itself

Abstract

The IMPORTANCE: Cryptococcosis is a systemic fungal infection that causes approximately 1 million cases globally, leading to approximately 625,000 annual deaths. Two species are responsible for the majority of cases,

Indexed as

CryptococcosisCryptococcus neoformansFungal CapsulesPolysaccharidesAnimalsCytokinesDendritic CellsDisease Models, AnimalFemaleLungMacrophagesMiceSerogroupVirulenceVirulence FactorsCytokinesglucuronoxylomannanPolysaccharidesVirulence Factorscapsular polysaccharidecapsuleCryptococcus neoformansexopolysaccharideextracellular polysaccharideglucuronoxylomannanGXMmotifspathogenesisvirulence

Identifiers

PMID41020608
PMCPMC12607832

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.