Evidence map›Paper›PMID 41020594›Full record

ArticleApplied and environmental microbiology2025

Hijacking anaerobic metabolism to restore antibiotic efficacy in

Zealon Gentry-Lear, Celine Lopez Padilla, Melanie A Spero

Abstract read
In one paragraph

Article in Applied and environmental microbiology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Zealon Gentry-Lear *Institute of Molecular Biology, University of Oregon, Eugene, Oregon, USA.
Celine Lopez Padilla *Institute of Molecular Biology, University of Oregon, Eugene, Oregon, USA.
Melanie A SperoInstitute of Molecular Biology, University of Oregon, Eugene, Oregon, USA.ORCID 0000-0003-3291-2138

Funding

Nutrient-driven bacterial physiology in recalcitrant infections.R35GM155575 · NIGMS · UNIVERSITY OF OREGON · PI Melanie A. Spero · 2024 to 2026
$1.1M
Collins Medical TrustCystic Fibrosis Foundation SPERO19F0Donald E. and Delia B. Baxter FoundationNIGMS NIH HHS R35 GM155575NIH HHS R35GM155575University of Oregon Mentored Research ProgramUniversity of Oregon VPRI Undergraduate Fellowship
6 · The paper itself

Abstract

Bacterial pathogens regularly encounter oxygen (O

Indexed as

Anti-Bacterial AgentsChloratesPseudomonas aeruginosaAnaerobiosisMicrobial Sensitivity TestsNitratesOxygenAnti-Bacterial AgentsChloratesNitratesOxygenanaerobic metabolismantibiotic potentiationantibiotic tolerancechloratenitrate respirationsynergy

Identifiers

PMID41020594
PMCPMC12542746

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.