Evidence map›Paper›PMID 41020545›Full record

ArticleKnee surgery, sports traumatology, arthroscopy : official journal of the ESSKA2026

Dynamic computed tomography assessment of patellofemoral and tibiofemoral kinematics before and after total knee arthroplasty: A pilot study.

Miriam R Boot, Sebastiaan A W van de Groes, Esther Tanck, Dennis Janssen

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Article in Knee surgery, sports traumatology, arthroscopy : official journal of the ESSKA, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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4 · The record

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5 · Who and what money

Authors and funding

4 authors.

Miriam R BootOrthopaedic Research Laboratory, Department of Orthopaedics, Radboud University Medical Center, Nijmegen, The Netherlands.ORCID https://orcid.org/0000-0003-0442-1091
Sebastiaan A W van de GroesOrthopaedic Research Laboratory, Department of Orthopaedics, Radboud University Medical Center, Nijmegen, The Netherlands.ORCID https://orcid.org/0000-0002-1254-9071
Esther TanckOrthopaedic Research Laboratory, Department of Orthopaedics, Radboud University Medical Center, Nijmegen, The Netherlands.ORCID https://orcid.org/0000-0002-3263-0045
Dennis JanssenOrthopaedic Research Laboratory, Department of Orthopaedics, Radboud University Medical Center, Nijmegen, The Netherlands.ORCID https://orcid.org/0000-0003-0743-9975

Funding

Smith and Nephew
6 · The paper itself

Abstract

purposeTo develop and evaluate the clinical feasibility of a dynamic computed tomography (CT) protocol for assessing patellofemoral (PF) and tibiofemoral (TF) kinematics before and after total knee arthroplasty (TKA), and to quantify postoperative kinematic changes in a pilot study.

methodsIn this prospective single-centre study, patients with primary osteoarthritis scheduled for cemented TKA underwent dynamic CT scans preoperatively and at 1-year follow-up during active flexion-extension-flexion. Preoperatively, the femur, tibia and patella were segmented using a neural network. Postoperatively, computer-aided design (CAD) implant models were aligned to CT data to determine relative implant-bone orientation. Due to metal artefacts, preoperative patella meshes were manually aligned to postoperative scans by four raters, and averaged for analysis. Anatomical coordinate systems were applied to quantify patellar flexion, tilt, proximal tip rotation, mediolateral translation and femoral condyle anterior-posterior translation. Descriptive statistics were reported, and interoperator agreement for patellar registration was assessed using intraclass correlation coefficients (ICCs).

resultsTen patients (mean age, 65 ± 8 years; 6 men) were analysed across a shared flexion range of 14°-55°. Postoperatively, the patella showed increased flexion (median difference: 0.9°-3.9°), medial proximal tip rotation (median difference: 1.5°-6.0°), lateral tilt (median difference: 2.7°-5.5°), and lateral shift (median difference: -1.5 to -2.8 mm). The medial and lateral femoral condyles translated 2-4 mm anterior-posteriorly during knee flexion. Interoperator agreement for patellar registration ranged from good to excellent across all parameters (ICC = 0.85-1.00).

conclusionThis pilot study demonstrates that dynamic CT enables in vivo assessment of PF and TF kinematics before and after TKA. The protocol quantified postoperative kinematic changes and demonstrated potential as research tool. Further automation is needed to investigate relationships between these kinematic patterns and patient outcomes in larger-scale studies. LEVEL OF EVIDENCE: Level III.

Indexed as

Arthroplasty, Replacement, KneeOsteoarthritis, KneePatellofemoral JointTibiofemoral JointTomography, X-Ray ComputedAgedBiomechanical PhenomenaFeasibility StudiesFemaleHumansMaleMiddle AgedPilot ProjectsProspective StudiesRange of Motion, ArticularTibiadynamic computed tomographykinematicskneepatellar trackingtotal knee arthroplasty

Identifiers

PMID41020545
PMCPMC13266916

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.