ArticleFrontiers in medicine2025
Clinical characteristics of endometriosis with and without dysmenorrhea diagnosed by laparoscopy.
Article in Frontiers in medicine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 2 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
2 citing papers in PubMed.
- Clinical challenges and therapeutic strategies in women with endometriosis, deep infiltrating endometriosis, and/or adenomyosis undergoing assisted reproductive technologies: a narrative review.Frontiers in reproductive health · 2026Review
- Multi-omics profiling identifies an immunometabolic signature associated with endometriosis.Frontiers in endocrinology · 2026Article
Corrections and comments
- Erratum issued
Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Objective: This study aimed to delineate the clinical characteristics of endometriosis patients with dysmenorrhea and analyze the correlations between the presence, severity, and duration of dysmenorrhea and the severity of endometriosis. Methods: In this retrospective study, a total of 489 patients with endometriosis were enrolled who had undergone laparoscopic surgery or had been diagnosed with endometriosis during surgery for benign ovarian tumors. The patients were categorized into dysmenorrhea-positive and dysmenorrhea-negative groups based on the presence of symptoms at diagnosis. Subgroup analyses were further performed within the dysmenorrhea group based on pain severity (mild/moderate/severe) and duration (years). The impact of dysmenorrhea on endometriosis severity was evaluated using clinical, surgical, and histopathological parameters. Results: The proportion of patients without dysmenorrhea was 29.4%, while the proportion of patients with dysmenorrhea was 70.6%. Patients with dysmenorrhea were found to be younger, had significantly higher CA125 levels, and had a higher surgical stage. Patients with dysmenorrhea were observed to be more likely to experience infertility and deep infiltrating nodules. Elevated CA125 levels and infiltrating nodules were found to be independent risk factors for dysmenorrhea. CA125 levels and surgical staging significantly increased with the severity of dysmenorrhea. CA199 levels increased with dysmenorrhea duration but decreased in patients with >10 years of symptoms. The longer the duration of dysmenorrhea, the more frequently adenomyosis was observed. Conclusion: The presence, severity, and prolonged duration of dysmenorrhea are strongly associated with advanced endometriosis, infertility, and adenomyosis. Young women with dysmenorrhea warrant heightened clinical suspicion for endometriosis to avoid delayed diagnosis.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.