SynthesisFrontiers in medicine2025
Nonpharmacologic treatment for elderly with constipation: a systematic review and meta-analysis.
Synthesis in Frontiers in medicine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
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Authors and funding
9 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Objective: This study evaluated the efficacy and safety of non-pharmacological interventions such as acupuncture, abdominal massage, ear acupoints, probiotics, and dietary fiber in the treatment of constipation in the elderly. Methods: Randomized controlled trials (RCTs) published up to March 2025 were retrieved from Cochrane Library, PubMed, Web of Science, Embase, and Chinese databases. The research quality was evaluated using the Cochrane risk of bias assessment tool. Data analysis was performed using RevMan5.4.1 and Stata software. Grade evidence quality was assessed on the analysis's outcome indicators. Results: Forty-one studies involving 3,005 patients aged ≥60 years were included. The non-pharmacologic treatment group demonstrated significantly higher efficacy compared to the control group (RR = 1.15, 95% CI = 1.09 to 1.21, Conclusion: Non-pharmaceutical interventions are better than conventional treatments in the treatment of constipation in the elderly, and long-term intervention has more significant effects. However, due to different intervention regimens, inconsistent treatment time, and methodological defects included in the study, there is a high degree of heterogeneity (CQLS, Bristol, and I
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