ArticleInfection and drug resistance2025
Evaluation of Serum Ischemia-Modified Albumin And Oxidative Stress Markers in Patients with Sepsis.
Article in Infection and drug resistance, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
1 citing paper in PubMed.
- A Machine Learning Model Integrating Systemic Immune-Inflammation Index for Predicting 28-Day Mortality in Geriatric Sepsis Secondary to Community-Acquired Bacterial Pneumonia.Clinical interventions in aging · 2026Article
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Authors and funding
4 authors.
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No grant is acknowledged in the PubMed record.
Abstract
Purpose: The most common causes of mortality and morbidity in patients followed up in intensive care are bacterial infections and sepsis. Rapid and timely intervention is essential for the successful treatment of sepsis. Therefore, this study aimed to reveal the relationships between mortality and patients by examining ıschemia-modified albumin, APACHE II, CRP, PCT, lactate, WBC, NLR, PLR, SII, platelet, and lactate/IMA (LIMA) values in patients with sepsis followed up in intensive care units. Material Method: The study was planned as prospective and single-center. 31 patients diagnosed with sepsis were included in the study. The first 24 hours and 5th day values of patients diagnosed with sepsis were examined and recorded. The biomarkers and APACHE-II score of patients diagnosed with sepsis were examined for predictive power of 28-day mortality. Results: Thirty-one patients diagnosed with sepsis from the Anesthesia Intensive Care Unit were included in the study. Of the total patients, 21 (67.7%) were male and 10 (32.3%) were female. The APACHE-II score of patients diagnosed with sepsis in the first 24 hours (AUC:0.891, 95% CI: 77.6-100, p<0.0001) was determined to be the best indicator for predicting 28-day mortality. In addition, neutrophil/lymphocyte ratio on day 5 (AUC:0.765, 95% CI:59.3-93.7, p:0.013), Lactate/IMA on day 1 (AUC:0.628, 95% CI:59.3-83.9, p:0.230) and SII on day 5 (AUC:0.624, 95% CI:42.3-82.5, p:0.246) were also determined as other biomarkers that can be used to predict 28-day mortality. Conclusion: APACHE-II score still maintains its place in predicting mortality in patients with sepsis. No biomarker alone has been able to surpass this score, and markers obtained in combination such as NLR, LIMA and SII may be helpful in predicting mortality. New and large-scale studies are needed on this subject.
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