Evidence map›Paper›PMID 41019913›Full record

SynthesisDepression and anxiety2025

A Systematic Review of Factors Associated With Treatment Engagement and Outcome for Women in the Perinatal Period Receiving Individual Cognitive Behavioral Therapy (CBT) for Depression, Anxiety, and Trauma-Related Disorders.

Natalie A Simon, Jenna Evans, Darcy Bispham, Ffion Williams, Jonathan Jones, Neil P Roberts, Cerith S Waters

Erratum issuedAbstract readSystematic Review
In one paragraph

Synthesis in Depression and anxiety, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 2 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

7 authors.

Natalie A SimonSouth Wales Clinical Psychology Training Program, School of Psychology, Cardiff University, Cardiff, Wales, UK.ORCID 0000-0001-5712-9460
Jenna EvansPerinatal Community Mental Health Service, Cardiff and Vale UHB, Cardiff, Wales, UK.
Darcy BisphamPerinatal Community Mental Health Service, Cardiff and Vale UHB, Cardiff, Wales, UK.
Ffion WilliamsPerinatal Community Mental Health Service, Cardiff and Vale UHB, Cardiff, Wales, UK.
Jonathan JonesPerinatal Community Mental Health Service, Cardiff and Vale UHB, Cardiff, Wales, UK.
Neil P RobertsDivision of Psychological Medicine and Clinical Neuroscience, Cardiff University, Cardiff, Wales, UK.ORCID 0000-0002-6277-0102
Cerith S WatersSouth Wales Clinical Psychology Training Program, School of Psychology, Cardiff University, Cardiff, Wales, UK.ORCID 0000-0002-7049-9906

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Depression, anxiety, and trauma-related disorders commonly occur in the perinatal period, with high rates of comorbidity, and potentially adverse outcomes for women and children. Cognitive behavioral therapy (CBT) is an effective treatment, however less than half of new mothers experiencing symptoms seek treatment. This review was focused on factors affecting treatment engagement and outcome in a clinical perinatal population. A mixed-methods systematic review was conducted according to Cochrane Collaboration Guidelines. We included randomized controlled trials (RCTs) of individual CBT where at least 70% of women met diagnostic criteria for depression, anxiety, or trauma-related disorders during the perinatal period. Information on, and factors associated with treatment engagement, satisfaction, therapeutic alliance were examined as risk ratios (RRs). Twenty-eight studies relating to 19 RCTs, with 2557 participants were reviewed. Most studies examined CBT adapted to the perinatal context. Engagement was good overall, and high levels of satisfaction and therapeutic alliance were reported. A relationship was demonstrated between engagement and outcome in three studies. Dropout did not differ for studies of CBT compared to treatment as usual (TAU), but there was greater dropout for CBT across four studies where the guiding therapist/coach had a minimal level of psychological therapy training and qualifications (

Indexed as

Anxiety DisordersCognitive Behavioral TherapyDepressive DisorderPregnancy ComplicationsTrauma and Stressor Related DisordersFemaleHumansPregnancyRandomized Controlled Trials as Topic

Identifiers

PMID41019913
PMCPMC12463511

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.