ArticleJournal of the Society for Cardiovascular Angiography & Interventions2025
2025 SCAI Clinical Practice Guidelines for the Management of Chronic Venous Disease: This statement was endorsed by the Society for Vascular Medicine (SVM).
Article in Journal of the Society for Cardiovascular Angiography & Interventions, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
9 citing papers in PubMed.
- The Wound-Heart Axis: Can Chronic Wounds Contribute to Cardiac Dysfunction?International journal of molecular sciences · 2026Review
- Quality-of-life outcomes after varicose vein surgery: A 12-month prospective study of 605 patients identifying key prognostic factors.Journal of vascular surgery. Venous and lymphatic disorders · 2026Article
- Quantitative duplex ultrasound assessment of superficial venous incompetence: A state-of-the-art review.Vascular medicine (London, England) · 2026Review
- A New Pearl in Chronic Venous Disease Pathophysiology-The Duplex Ultrasound and the Elastographic Features of Lymph Nodes Varicose Veins in the Groin.Diagnostics (Basel, Switzerland) · 2026Article
- Predictive value of great and small saphenous vein diameters for venous reflux in lower extremity chronic venous insufficiency: A segmental analysis using duplex ultrasonography.Journal of ultrasound · 2026Article
- Non-thermal venous endothelial injury by microsecond irreversible electroporation: mechanisms of apoptosis, oxidative stress, and vascular closure initiation.Frontiers in cell and developmental biology · 2026Article
- Benchmarking public large language model responses to patient-facing varicose veins questions: informational quality, verifiability indicators, and readability.Frontiers in public health · 2026Article
- Article
- Charting the Course and Uncharted Territories: SCAI 2025 Guidelines for Chronic Venous Disease.Journal of the Society for Cardiovascular Angiography & Interventions · 2025Article
Corrections and comments
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Authors and funding
20 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Background: Chronic venous disease (CVD) is a common vascular condition that can have debilitating effects on quality of life and daily function. The Society for Cardiovascular Angiography & Interventions (SCAI) sought to develop evidence-based guidelines to support patients, clinicians, and other stakeholders in their treatment decisions about management of CVD. Methods: SCAI convened a balanced multidisciplinary guideline panel to minimize potential bias from conflicts of interest. The Evidence Foundation, a registered 501(c)(3) nonprofit organization, provided methodological support for the development of the guidelines. The guideline panel formulated and prioritized clinical questions following the Grading of Recommendations Assessment, Development and Evaluation (GRADE) approach in population, intervention, comparison, outcome format. A technical review team of clinical and methodological experts conducted systematic reviews of the published evidence, synthesized data, and graded the certainty of the evidence across outcomes. The guideline panel then reconvened to develop recommendations and supporting remarks informed by the results of the technical review, as well as additional contextual factors described in the GRADE evidence-to-decision framework. Results: The guideline panel reached consensus on 9 recommendations to address variations in treatment of CVD across 8 different clinical scenarios. The panel also identified 4 anatomical scenarios with significant knowledge gaps. Conclusions: Key recommendations address patient selection for compression therapy, ablation of saphenous and perforator veins, sclerotherapy, phlebectomy, and deep vein revascularization. Two algorithms for the management of symptomatic varicose veins and venous ulcer disease were created to facilitate implementation of these evidence-based recommendations. The panel also identified several anatomical and clinical areas where future research is needed to advance the CVD field.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.