Evidence map›Paper›PMID 41019881›Full record

ArticleClinical psychological science : a journal of the Association for Psychological Science2025

Characterizing midlife-onset alcohol dependence: Implications for etiology, prevention, and healthy aging.

Lara Khalifeh, Avshalom Caspi, Kallisse R Dent, HonaLee Harrington, Madeline H Meier, Richie Poulton, Sandhya Ramrakha, Terrie E Moffitt, Leah S Richmond-Rakerd

Abstract read
In one paragraph

Article in Clinical psychological science : a journal of the Association for Psychological Science, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Major depressive disorder-alcohol use disorder comorbidity: diagnosis, mechanisms and treatment.European archives of psychiatry and clinical neuroscience · 2026
    Review
  2. Article
  3. Mental health impacts of climate-related hazards among farmers: evidence from a community-based study.Journal of occupational medicine and toxicology (London, England) · 2026
    Article
  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Lara KhalifehDepartment of Psychology, University of Michigan, Ann Arbor, MI 48109.
Avshalom CaspiDepartment of Psychology and Neuroscience, Duke University, Durham, NC 27708.
Kallisse R DentDepartment of Psychology, University of Michigan, Ann Arbor, MI 48109.
HonaLee HarringtonDepartment of Psychology and Neuroscience, Duke University, Durham, NC 27708.
Madeline H MeierDepartment of Psychology, Arizona State University, Tempe, AZ 85281.
Richie PoultonDunedin Multidisciplinary Health and Development Research Unit, Department of Psychology, University of Otago, Dunedin, NZ.
Sandhya RamrakhaDunedin Multidisciplinary Health and Development Research Unit, Department of Psychology, University of Otago, Dunedin, NZ.
Terrie E MoffittDepartment of Psychology and Neuroscience, Duke University, Durham, NC 27708.
Leah S Richmond-RakerdDepartment of Psychology, University of Michigan, Ann Arbor, MI 48109.

Funding

Is mental disorder a preventable cause of age-related disease? The Dunedin Study.R01AG032282 · NIA · DUKE UNIVERSITY · PI CASPI, AVSHALOM, MOFFITT, TERRIE E · 2009 to 2025
$9.5M
Comprehensive portrait of long-term cannabis users: Are they ready for old age?R01AG069939 · NIA · DUKE UNIVERSITY · PI MOFFITT, TERRIE E · 2021 to 2024
$1.3M
NIA NIH HHS R01 AG032282NIA NIH HHS R01 AG069939
6 · The paper itself

Abstract

We evaluated the developmental epidemiology of midlife-onset alcohol dependence (AD) in the Dunedin Study (

Identifiers

PMID41019881
PMCPMC12467522

What OpenQuestion holds

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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.