Evidence map›Paper›PMID 41019878›Full record

ArticleSage open pediatrics

Prevalence of Hypothalamic-Pituitary Abnormalities in Pediatric Patients with Growth Hormone Deficiency.

Giorgio Sodero, Luigi Antonio Moscogiuri, Marilea Lezzi, Fabio Comes, Paola Passoforte, Giacomo Perrone, Aniello Meoli, Anna Camporeale, Antonietta Villirillo, Francesco Gallo

Abstract read
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In one paragraph

Article in Sage open pediatrics. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Giorgio SoderoPediatric Unit, Azienda Sanitaria Locale di Brindisi, Perrino Hospital, Italy.ORCID https://orcid.org/0000-0003-3711-4928
Luigi Antonio MoscogiuriPediatric Unit, Azienda Sanitaria Locale di Brindisi, Perrino Hospital, Italy.
Marilea LezziPediatric Unit, Azienda Sanitaria Locale di Brindisi, Perrino Hospital, Italy.
Fabio ComesPediatric Unit, Azienda Sanitaria Locale di Brindisi, Perrino Hospital, Italy.
Paola PassofortePediatric Unit, Azienda Sanitaria Locale di Brindisi, Perrino Hospital, Italy.
Giacomo PerronePediatric Unit, Azienda Sanitaria Locale di Brindisi, Perrino Hospital, Italy.
Aniello MeoliPediatric Unit, Azienda Sanitaria Locale di Brindisi, Perrino Hospital, Italy.
Anna CamporealePediatric Unit, Azienda Sanitaria Locale di Brindisi, Perrino Hospital, Italy.
Antonietta VillirilloPediatric Unit, Azienda Sanitaria Locale di Brindisi, Perrino Hospital, Italy.
Francesco GalloPediatric Unit, Azienda Sanitaria Locale di Brindisi, Perrino Hospital, Italy.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Growth hormone deficiency (GHD) is a key differential diagnosis in children with proportionate short stature. While brain magnetic resonance imaging (MRI) is recommended for all confirmed GHD cases to rule out hypothalamic-pituitary anomalies, its universal application remains debated We conducted a retrospective, single-center study including 84 pediatric patients diagnosed with isolated GHD Brain MRI revealed hypothalamic-pituitary abnormalities in 27.4%. Compared to those with normal MRIs, patients with abnormalities were younger (6.78 ± 2.72 vs 8.34 ± 3.38 years,

Indexed as

adolescent medicineendocrinologygrowth hormonegrowth hormone deficiencypediatric endocrinology

Identifiers

PMID41019878
PMCPMC12464405

What OpenQuestion holds

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LicenceCC BY-NC
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.