ReviewRSC advances2025
Strategic engineering of carbon dots: multi-enzyme mimetics for advanced biomedical intervention in oxidative stress-related diseases.
Review in RSC advances, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
4 citing papers in PubMed.
- Bioinspired zinc-doped carbon dots protect against polystyrene microplastic-induced spermatogenic dysfunction through Nrf2 activation and cuproptosis suppression.Materials today. Bio · 2026Article
- Marine-derived carbon dots: a safe and effective solution for noise-induced hearing loss.Journal of nanobiotechnology · 2026Article
- Metal-Functionalized Nanozymes in Antibacterial Wound Management: Recent Advances and Future Perspectives.Pharmaceuticals (Basel, Switzerland) · 2026Review
- Novel Carbon Dots Nanomaterials for the Precision Diagnosis and Treatment of Acute Lung Injury and Acute Respiratory Distress Syndrome: Mechanisms and Applications.International journal of nanomedicine · 2026Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Carbon dots (CDs), an emerging class of carbon-based nanomaterials, have garnered significant attention due to their tunable physicochemical properties, biocompatibility, and versatile enzyme-mimicking activities. This review systematically explores recent advances in the rational design of CDs for combating oxidative stress-related pathologies. Key strategies include heteroatom doping, selection of bioactive precursors, and utilization of sustainable biomaterials. Doping with Se, Fe, or N enhances reactive oxygen/nitrogen species (RONS) scavenging, peroxidase, catalase, or superoxide dismutase like activities, enabling applications in acute kidney injury, ulcerative colitis, and Parkinson's disease. CDs derived from natural compounds inherit intrinsic antioxidant and anti-inflammatory properties, facilitating gut microbiota regulation, diabetic wound healing, and periodontitis treatment. Notably, stimuli-responsive CDs dynamically modulate multi-enzyme activities, preventing RONS overproduction and enabling precise therapy. This work highlights the synergy between structural engineering and bioactivity preservation in CDs, positioning them as next generation nanotherapeutics for inflammatory, infectious, and degenerative diseases.
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.