ArticleNational journal of maxillofacial surgery
Clinicoradiographic evaluation of polymer of injectable platelet rich fibrin (i-PRF) and hydroxyapatite as bone graft substitute in maxillomandibular bony defects: A double blinded randomised control trial.
Article in National journal of maxillofacial surgery. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
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Who cites it
1 citing paper in PubMed.
- The tooth transformer® revolution: autologous dentin biomaterials and platelet concentrates in oral regeneration. A parallel narrative systematic review.Frontiers in dental medicine · 2025Review
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Authors and funding
6 authors.
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Abstract
Purpose: Enucleation of the maxillo-mandibular cysts will create post-surgical bone defects, which may take more than a year for complete bone healing. Bone grafts are common to aid bone regeneration in large defects. The aim was to evaluate the clinical and radiographical healing and bone formation capabilities of polymer of i-PRF and hydroxyapatite in maxilla-mandibular defects compared to hydroxyapatite (HA) alone. The primary objective was to do a clinical assessment of healing at postoperative days 1, 3, and 7; and a radiological evaluation of bone formation postoperatively at the 2 Material and Methods: After surgical enucleation of 19 maxillo-mandibular cysts/tumors, either HA or HA + i-PRF graft was adapted to the defect. Clinical outcome variables such as Pain (VAS score), edema, and mucosal color were evaluated on postoperative days 01, 03, and 07 while radiological outcome variables such as volume of the defect (cc), and Density of new bone (HU) on Computed Tomography were evaluated at 2 Results: Clinical parameters are better in the HA + i-PRF group but the result was non-significant. Radiologically, the mean healing ratios were significantly greater in the HA + i-PRF group (63.5 ± 2.34 at 2 Conclusion: The polymer of i-PRF and HA prepared as the sticky bone yields faster and better bone healing in post-enucleation maxilla-mandibular bony defects as compared to hydroxyapatite alone based on radiological findings till 4 months.
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