Evidence map›Paper›PMID 41019618›Full record

ArticleACS physical chemistry Au2025

Understanding the Binding and Structures in Model Complexes of Polypeptides and Cofactors.

Yinan Li, Kenny K Y Lun, Justin Kai-Chi Lau, Jonathan Martens, Giel Berden, Jos Oomens, Alan C Hopkinson, K W Michael Siu, Ivan K Chu

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In one paragraph

Article in ACS physical chemistry Au, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Yinan LiCenter for Mass Spectrometry Research and Clinical Application, Shandong Public Health Clinical Center Affiliated to Shandong University, 46 Lishan Road, Shandong, Jinan 250012, China.
Kenny K Y LunDepartment of Chemistry, University of Hong Kong, Hong Kong, China.
Justin Kai-Chi LauDepartment of Chemistry, York University, 4700 Keele Street, Toronto, ON M3J 1P3, Canada.ORCID https://orcid.org/0000-0001-8327-0644
Jonathan MartensFELIX Laboratory, Institute for Molecules and Materials, Radboud University, Toernooiveld 7, ED Nijmegen 6525, the Netherlands.ORCID https://orcid.org/0000-0001-9537-4117
Giel BerdenFELIX Laboratory, Institute for Molecules and Materials, Radboud University, Toernooiveld 7, ED Nijmegen 6525, the Netherlands.ORCID https://orcid.org/0000-0003-1500-922X
Jos OomensFELIX Laboratory, Institute for Molecules and Materials, Radboud University, Toernooiveld 7, ED Nijmegen 6525, the Netherlands.
Alan C HopkinsonDepartment of Chemistry, York University, 4700 Keele Street, Toronto, ON M3J 1P3, Canada.ORCID https://orcid.org/0000-0002-5169-2970
K W Michael SiuCenter for Mass Spectrometry Research and Clinical Application, Shandong Public Health Clinical Center Affiliated to Shandong University, 46 Lishan Road, Shandong, Jinan 250012, China.ORCID https://orcid.org/0000-0002-9551-6506
Ivan K ChuCenter for Mass Spectrometry Research and Clinical Application, Shandong Public Health Clinical Center Affiliated to Shandong University, 46 Lishan Road, Shandong, Jinan 250012, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Competitive binding between metal cofactors and functional groups of polypeptides results in a diversity of structures and chemistries in metalloproteins. Herein, we examined elements of this competitive binding using [metal-(auxiliary ligand)-(peptide)] complexes, where the metal-(auxiliary ligand) combinations are Cu

Indexed as

competitive binding and structuresdensity functional theory calculationselectrospray tandem mass spectrometryhard/soft Lewis acids/basesinfrared multiple-photon dissociation (IRMPD) spectroscopyintrinsic acid−base chemistry[metal(auxiliary ligand)(peptide)] complexes

Identifiers

PMID41019618
PMCPMC12464774

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.