Evidence map›Paper›PMID 41019528›Full record

ReviewFrontiers in microbiology2025

Advancements in research leveraging phage display technology for gastric cancer diagnosis and treatment.

Zhenyu Wang, Yuping Li, Jun Lin, Fuyu Deng, Yao Liu, Yuan Ji

Abstract readReview
In one paragraph

Review in Frontiers in microbiology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Zhenyu Wang *Shenzhen Institute for Drug Control Shenzhen Testing Center of Medical Devices, Shenzhen, China.
Yuping Li *Shenzhen Institute for Drug Control Shenzhen Testing Center of Medical Devices, Shenzhen, China.
Jun LinShenzhen Institute for Drug Control Shenzhen Testing Center of Medical Devices, Shenzhen, China.
Fuyu DengShenzhen Institute for Drug Control Shenzhen Testing Center of Medical Devices, Shenzhen, China.
Yao LiuShenzhen Institute for Drug Control Shenzhen Testing Center of Medical Devices, Shenzhen, China.
Yuan JiShenzhen Institute for Drug Control Shenzhen Testing Center of Medical Devices, Shenzhen, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Gastric cancer persists as a major global health challenge, ranking among the leading causes of cancer-related deaths worldwide. The high mortality rate primarily stems from difficulties in early detection, often resulting in late-stage diagnosis when treatment options are limited. Phage display technology, developed in 1985, has emerged as a powerful tool in gastric cancer research, facilitating significant advances in three key areas: (1) identification of novel biomarkers for early detection, (2) screening of targeted therapeutic molecules, and (3) development of diagnostic reagents. This comprehensive review examines current applications of phage display in both diagnostic and therapeutic approaches for gastric cancer, while critically analyzing existing limitations in sensitivity, specificity, library diversity, and screening efficiency. Furthermore, we discuss the promising potential of integrating phage display with other cutting-edge technologies, proposing future research directions that could enhance its clinical utility and ultimately improve patient outcomes in gastric cancer management.

Indexed as

biomarkerdiagnosisgastric cancerphage displaytargetingTreatment

Identifiers

PMID41019528
PMCPMC12466155

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.