Evidence map›Paper›PMID 41019482›Full record

ArticleExperimental and therapeutic medicine2025

A rare splenic and pancreatic inflammatory myofibroblastic tumour with left-sided portal hypertension and gastric varices: A case report.

Eleni Zografos, Alkistis Papatheodoridi, Maria Kaparelou, Ioanna Tatouli, Andreas Mpozikas, Margarita Papatheodoridi, Angeliki Andrikopoulou, Constantinos G Zografos, Georgia Kafiri, Efstathios Manios and 2 more

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Article in Experimental and therapeutic medicine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

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2 · The registry

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3 · Its place in the literature

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4 · The record

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5 · Who and what money

Authors and funding

12 authors.

Eleni ZografosDepartment of Clinical Therapeutics, Alexandra General Hospital, Medical School of the National and Kapodistrian University of Athens, 11528 Athens, Greece.
Alkistis PapatheodoridiDepartment of Clinical Therapeutics, Alexandra General Hospital, Medical School of the National and Kapodistrian University of Athens, 11528 Athens, Greece.
Maria KaparelouDepartment of Clinical Therapeutics, Alexandra General Hospital, Medical School of the National and Kapodistrian University of Athens, 11528 Athens, Greece.
Ioanna TatouliDepartment of Clinical Therapeutics, Alexandra General Hospital, Medical School of the National and Kapodistrian University of Athens, 11528 Athens, Greece.
Andreas MpozikasDepartment of Clinical Therapeutics, Alexandra General Hospital, Medical School of the National and Kapodistrian University of Athens, 11528 Athens, Greece.
Margarita PapatheodoridiAcademic Department of Gastroenterology, Medical School of National and Kapodistrian University of Athens, Laiko General Hospital, 11527 Athens, Greece.
Angeliki AndrikopoulouDepartment of Clinical Therapeutics, Alexandra General Hospital, Medical School of the National and Kapodistrian University of Athens, 11528 Athens, Greece.
Constantinos G ZografosSecond Department of Surgery, 'Aretaieio' Hospital, 11528 Athens, Greece.
Georgia KafiriDepartment of Pathology, 'Hippocrateio' General Hospital of Athens, 11527 Athens, Greece.
Efstathios ManiosDepartment of Clinical Therapeutics, Alexandra General Hospital, Medical School of the National and Kapodistrian University of Athens, 11528 Athens, Greece.
Meletios-Athanasios DimopoulosDepartment of Clinical Therapeutics, Alexandra General Hospital, Medical School of the National and Kapodistrian University of Athens, 11528 Athens, Greece.
Flora ZagouriDepartment of Clinical Therapeutics, Alexandra General Hospital, Medical School of the National and Kapodistrian University of Athens, 11528 Athens, Greece.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Left-sided portal hypertension or segmental portal hypertension is a rare cause of upper gastrointestinal bleeding. The present study reports a case of isolated gastric variceal haemorrhage and hypersplenism, due to left-sided portal hypertension induced by inflammatory myofibroblastic tumour (IMT)-associated splenic vein compression. IMT is an rare mesenchymal neoplasm of intermediate malignant potential that can develop in any location, frequently remaining entirely asymptomatic until it reaches a size that leads to complications. To the best of our knowledge, this is the first case reported of an IMT involving both the spleen and the pancreas. In this patient, splenectomy and partial pancreatectomy were both diagnostic and curative for IMT, and no adjuvant therapy was followed. This case report, along with a short review of the current knowledge on IMT features, contributes towards the understanding and diagnosis of this rare entity with diverse clinical presentations.

Indexed as

bleedinghypersplenisminflammatory myofibroblastic tumourisolated gastric varicesleft-sided portal hypertensionpancreasspleen

Identifiers

PMID41019482
PMCPMC12464477

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