Evidence map›Paper›PMID 41019312›Full record

ReviewCurrent ophthalmology reports2025

3D Bioprinting of Cellular Therapeutic Systems in Ophthalmology: from Bioengineered Tissue to Personalized Drug Delivery.

Hyeonji Kim, Gia-Han Ngo, Wen Hong, Soo Hyeon Lee, Vinit B Mahajan, Charles DeBoer

Abstract readReview
In one paragraph

Review in Current ophthalmology reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Review
  2. Review
  3. 3D Bioprinting Strategies in Autoimmune Disease Models.International journal of molecular sciences · 2025
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Hyeonji KimDepartment of Ophthalmology, School of Medicine, Byers Eye Institute at Stanford University, Palo Alto, CA 94304 USA.
Gia-Han NgoDepartment of Ophthalmology, School of Medicine, Byers Eye Institute at Stanford University, Palo Alto, CA 94304 USA.
Wen HongDepartment of Ophthalmology, School of Medicine, Byers Eye Institute at Stanford University, Palo Alto, CA 94304 USA.
Soo Hyeon LeeDepartment of Ophthalmology, School of Medicine, Byers Eye Institute at Stanford University, Palo Alto, CA 94304 USA.
Vinit B MahajanDepartment of Ophthalmology, School of Medicine, Byers Eye Institute at Stanford University, Palo Alto, CA 94304 USA.
Charles DeBoerDepartment of Ophthalmology, School of Medicine, Byers Eye Institute at Stanford University, Palo Alto, CA 94304 USA.

Funding

Stanford Vision Research CoreP30EY026877 · NEI · STANFORD UNIVERSITY · PI TIRIN MOORE · 2017 to 2026
$8.0M
Lens Capsule Based Extended Drug Delivery DeviceK08EY036955 · NEI · STANFORD UNIVERSITY · PI Charles Meno Theodore DeBoer · 2025 to 2026
$516k
NEI NIH HHS K08 EY036955NEI NIH HHS P30 EY026877
6 · The paper itself

Abstract

Purpose of Review: In this article, we provide a brief overview of 3D bioprinting technologies and the types of cells employed in ophthalmic cell therapy. We then explore recent applications of 3D bioprinting in ophthalmic cell delivery systems. Recent Findings: Cell therapy in ophthalmology is a promising treatment for various eye diseases, there exists some limitations of existing cell therapy strategies Such as cell loss, poor integration with Surrounding tissues, and the sustainability of long-term effects. In this regard, 3D bioprinting technology provides a beneficial method for developing highly biomimetic and reliable cell delivery systems for ophthalmic disease research. Recent advances have shown bioengineered tissues which replicate the microstructure of native tissues, personalized ophthalmic devices, and encapsulated cell-delivery systems. While still in the early stages of advancement, the development of cell delivery systems based on bioprinting technologies is indeed inspiring and has the potential to be applied to other ocular diseases. Summary: Cell therapy based on 3D bioprinting technology in ophthalmology has great potential in ophthalmic disease treatment as well as ocular tissue engineering and regenerative medicine.

Indexed as

3D bioprinting technologyCell therapyDrug deliveryRegenerative medicineTissue engineering

Identifiers

PMID41019312
PMCPMC12474738

What OpenQuestion holds

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LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.