ArticleBiochemistry and biophysics reports2025
Study on the effect of HMGB1 on immune cells isolated from SLE mice.
Article in Biochemistry and biophysics reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
2 citing papers in PubMed.
- Taking its TOLL: the role of toll-like receptor 4 in human health and disease, and its potential as a therapeutic target.Frontiers in immunology · 2026Review
- Dualistic Roles of High Mobility Group Box 1 in Cancer and Inflammation.Cancer medicine · 2025Review
Corrections and comments
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Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Systemic lupus erythematosus (SLE) is a complex autoimmune disease, and its pathogenesis is related to the balance and dysfunction of dendritic cells (DCs). The therapy targeting dendritic cells has become an important means to treat SLE and autoimmune diseases. Besides, HMGB1 is highly expressed in the serum of patients with SLE. Therefore, this study intended to find the function of HMGB1 on immune cells in SLE. We used the MRL/lpr mice as SLE model animals, then we isolated the peripheral blood of SLE mice to obtain CD14
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Registered trials
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