ArticleFrontiers in surgery2025
Immunomodulatory factors CRP/albumin ratio and NLR predict post-spinal surgery infection.
Article in Frontiers in surgery, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
Objective: The objective of this work is to investigate the predictive value of the neutrophil-to-lymphocyte ratio (NLR) combined with the C-reactive protein/albumin (CRP/ALB) ratio for postoperative infections in patients undergoing spinal surgery. Methods: According to the inclusion criteria, 380 patients who underwent spinal surgery treatment in the Sixth Affiliated Hospital of Xinjiang Medical University between January 2020 and December 2023 were retrospectively screened and divided into two groups based on whether they were infected after surgery. The two groups were 1. infected group ( Results: Comparative analysis revealed significant between-group differences ( Conclusion: The results indicate that age, duration of surgery, blood transfusion, internal fixation, postoperative NLR and postoperative CRP/ALB are risk factors for the development of infection after spinal surgery. Surgeons should perform a thorough assessment of their patients in order to more accurately predict their likelihood of infection and to provide a basis for individualised treatment plans to reduce the risk of postoperative infections.
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