Evidence map›Paper›PMID 41018868›Full record

ArticleJournal of pharmacopuncture2025

Quorum Sensing Inhibition and Virulence Factor Attenuation in

Farah Khader Al-Helo, Nasser El-Banna, Haitham Qaralleh, Muhamad O Al-Limoun, Khaled Khleifat

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of pharmacopuncture, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Farah Khader Al-HeloDepartment of Medical Laboratory Analysis, Faculty of Science, Al-Balqa Applied University, Al-Salt, Jordan.ORCID https://orcid.org/0009-0005-6850-8104
Nasser El-BannaDepartment of Medical Laboratory Analysis, Faculty of Science, Al-Balqa Applied University, Al-Salt, Jordan.ORCID https://orcid.org/0009-0009-4584-1018
Haitham QarallehDepartment of Medical Laboratory Sciences, Mutah University, Mutah, Jordan.ORCID https://orcid.org/0000-0002-9658-0040
Muhamad O Al-LimounDepartment of Biological Sciences, Faculty of Science, Mutah University, Mutah, Jordan.ORCID https://orcid.org/0000-0003-3015-7562
Khaled KhleifatDepartment of Medical Laboratory Sciences, Mutah University, Mutah, Jordan.ORCID https://orcid.org/0000-0002-0216-3175

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Objectives: This study aimed to assess the inhibitory effects of camphor on quorum sensing (QS), virulence factors, and biofilm formation in Methods: Results: The minimum biofilm inhibitory concentration (MBIC50) ranged between 125 and 63 µg/mL. Camphor significantly reduced biofilm formation and virulence factor production at all tested concentrations. It also decreased EPS synthesis, swarming motility, hydrophobicity, and cell aggregation. Camphor suppressed acyl homoserine lactone (AHL) production and downregulated QS genes, reducing Conclusion: Camphor demonstrates strong antibiofilm, antivirulence, and anti-QS activities against

Indexed as

biofilmcamphorPseudomonas aeruginosaquorum sensingvirulence factor

Identifiers

PMID41018868
PMCPMC12464080

What OpenQuestion holds

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LicenceCC BY-NC
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.