Evidence map›Paper›PMID 41018696›Full record

ArticleOpen forum infectious diseases2025

Changes in the Prevalence of Antimalarial Partner Drug Resistance Markers and Policy in 6 Sub-Saharan African Countries From 2000 to 2021: A Systematic Review.

Alexandra Walker, Amanda Ross, Christian Nsanzabana

Abstract read
In one paragraph

Article in Open forum infectious diseases, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. bioRxiv : the preprint server for biology · 2026
    Article
  3. Review
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Alexandra WalkerDepartment of Medicine, Swiss Tropical and Public Health Institute, Allschwil, Switzerland.ORCID https://orcid.org/0009-0004-4312-2830
Amanda RossDepartment of Medicine, Swiss Tropical and Public Health Institute, Allschwil, Switzerland.ORCID https://orcid.org/0000-0001-6027-5645
Christian NsanzabanaDepartment of Medicine, Swiss Tropical and Public Health Institute, Allschwil, Switzerland.ORCID https://orcid.org/0000-0002-6944-3892

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Prompt malaria case management is a cornerstone for malaria control and elimination. However, this strategy is threatened by the development of antimalarial drug resistance. Resistance is mediated through spontaneous genetic changes such as mutations, but drug pressure is the main driver of resistance spread. Molecular markers of resistance may provide insight into spatiotemporal dynamics of drug resistance and how drug policy changes may affect the spread of resistance. Methods: We conducted a systematic review to assess the dynamics of Results: Overall, 138 studies were included. The estimated prevalence of Conclusions: Our study provides compelling evidence on the impact of antimalarial drug policy change on molecular markers of resistance and their potential use to monitor drug resistance spread.

Indexed as

antimalarial drug policyantimalarial drug resistancesmolecular markersprevalencesystematic review

Identifiers

PMID41018696
PMCPMC12461838

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.