Evidence map›Paper›PMID 41018563›Full record

ArticleThe New England Journal of Statistics in Data Science2025

Practical Considerations for Variable Screening in the Super Learner.

Brian D Williamson, Drew King, Ying Huang

Abstract read
In one paragraph

Article in The New England Journal of Statistics in Data Science, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Brian D WilliamsonKaiser Permanente Washington Health Research Institute, Fred Hutchinson Cancer Center, and University of Washington, USA.
Drew KingSeattle Central College, USA.
Ying HuangFred Hutchinson Cancer Center and University of Washington, USA.

Funding

The Early Detection Research Network: Data Management and Coordinating CenterU24CA086368 · NCI · FRED HUTCHINSON CANCER RESEARCH CENTER · PI RUTH D ETZIONI, Ziding Feng · 2010 to 2026
$75.7M
Statistical Methods in HIV Vaccine Efficacy TrialsR37AI054165 · NIAID · FRED HUTCHINSON CANCER RESEARCH CENTER · PI Peter B. Gilbert · 2010 to 2026
$6.7M
High-Performance Compute Cluster for Comprehensive Cancer and Infectious Diseases ResearchS10OD028685 · OD · FRED HUTCHINSON CANCER RESEARCH CENTER · PI BRADLEY, PHILIP · 2020 to 2020
$2.0M
Statistical Methods for Selection and Evaluation of BiomarkersR01GM106177 · NIGMS · FRED HUTCHINSON CANCER RESEARCH CENTER · PI HUANG, YING · 2013 to 2018
$1.6M
Accelerating biomarker development through novel statistical methods for analyzing phase III/IV studiesR01CA277133 · NCI · FRED HUTCHINSON CANCER CENTER · PI Ying Huang · 2023 to 2026
$1.6M
NCI NIH HHS R01 CA277133NCI NIH HHS U24 CA086368NIAID NIH HHS R37 AI054165NIGMS NIH HHS R01 GM106177NIH HHS S10 OD028685
6 · The paper itself

Abstract

Estimating a prediction function is a fundamental component of many data analyses. The super learner ensemble, a particular implementation of stacking, has desirable theoretical properties and has been used successfully in many applications. Dimension reduction can be accomplished by using variable screening algorithms (screeners), including the lasso, within the ensemble prior to fitting other prediction algorithms. However, the performance of a super learner using the lasso for dimension reduction has not been fully explored in cases where the lasso is known to perform poorly. We provide empirical results that suggest that a diverse set of candidate screeners should be used to protect against poor performance of any one screener, similar to the guidance for choosing a library of prediction algorithms for the super learner. These results are further illustrated through the analysis of HIV-1 antibody data.

Indexed as

Ensemble machine learningPredictionSuper learnerVariable screening

Identifiers

PMID41018563
PMCPMC12462829

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.