ArticleDigital health
Efficacy and feasibility of virtual reality-based cognitive tele-rehabilitation in Parkinson's disease: A pilot randomized controlled trial on patients and caregivers.
Article in Digital health. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers, 6 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
6 citing papers in PubMed, 6 syntheses or guidelines pooled it.
- The Improvement Effects of Virtual Reality-Assisted Exercise Training on Motor and Psychiatric Symptoms in Patients With Parkinson's Disease: A Meta-Analysis of Randomized Controlled Trials.Actas espanolas de psiquiatria · 2026Pooled it
- Immersive Technologies for Cognitive Rehabilitation in Dementia and Mild Cognitive Impairment: Systematic Review.Journal of medical Internet research · 2026Pooled it
- Technologies used in Parkinson's disease: a meta-analysis of their effect on health-related quality of life.Journal of neurology · 2026Pooled it
- The Effects of Digital Health Interventions on Motor Symptoms, Nonmotor Symptoms, and Quality of Life in Patients With Parkinson Disease: Systematic Review and Meta-Analysis of Randomized Controlled Trials.Journal of medical Internet research · 2026Pooled it
- Virtual reality training for gait disorders in Parkinson's disease: a bibliometric and visual analysis of hotspots and trends using CiteSpace and VOSviewer.Frontiers in neurologyPooled it
- Effects of digital technology-based interventions on balance function and non-motor outcomes in Parkinson's disease: a systematic review and meta-analysis.Frontiers in neurologyPooled it
Corrections and comments
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Authors and funding
9 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Objective: Parkinson's disease (PD) is a progressive neurodegenerative disorder that not only impairs motor functions but also may lead to significant cognitive decline, greatly affecting the quality of life for both patients and their caregivers. This study aims to evaluate the feasibility and potential effectiveness of cognitive tele-rehabilitation (TR) plus virtual reality (VR), compared to traditional home-based rehabilitation methods, focusing on cognitive outcomes, quality of life, usability, and the impact on caregiver strain in patients with PD. Methods: In this pilot randomized controlled trial, 20 PD patients and their primary caregivers were randomly assigned to either a control group (CG) receiving traditional cognitive training or an experimental group (EG) undergoing cognitive TR using a VR rehabilitation system, with assessments conducted before and after the 8-week intervention. Results: TR was rated as highly usable (System Usability Scale mean score: 84.3 ± 9.5). Post-intervention analyses showed significant improvements in global cognitive functioning (Montreal Cognitive Assessment (MoCA): Conclusion: These findings suggest that cognitive TR, particularly when integrated with VR, might be useful in improving cognitive function and quality of life in PD patients and could play a key role in future PD management strategies, potentially easing the burden on caregivers.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.