Evidence map›Paper›PMID 41018295›Full record

ArticleCureus2025

Regional Anesthesia in a Cirrhotic Patient With Coagulopathy and Pulmonary Hypertension: A Case Report.

Angela Lu, Katherine Elsea, David A Olsen, Beth A VanderWielen

Abstract readCase Reports
In one paragraph

Article in Cureus, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Angela LuAnesthesiology and Perioperative Medicine, Mayo Clinic, Rochester, USA.
Katherine ElseaAnesthesiology and Perioperative Medicine, Mayo Clinic, Rochester, USA.
David A OlsenAnesthesiology and Perioperative Medicine, Mayo Clinic, Rochester, USA.
Beth A VanderWielenAnesthesiology and Perioperative Medicine, Mayo Clinic, Rochester, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

End-stage liver disease increases perioperative risk due to cirrhosis-related complications such as portal hypertension, coagulopathy, ascites, encephalopathy, and impaired anesthetic metabolism. Although regional anesthesia may reduce these risks compared to general anesthesia, its use is often limited in this population due to coagulopathy and altered drug metabolism. We present the successful use of an axillary brachial plexus block with bupivacaine for olecranon bursa excision in a 72-year-old man with ASA (American Society of Anesthesiologists) IV physical status classification and a MELD-Na (Model for End-Stage Liver Disease-Sodium) score of 15, complicated by coagulopathy, portal hypertension, and pulmonary hypertension. This case highlights the feasibility of regional anesthesia in high-risk cirrhotic patients with abnormal coagulation profiles.

Indexed as

axillary brachial plexus nerve blockcirrhosiscoagulopathyregional vs. general anesthesiaultrasound-guided regional anesthesiaupper limb orthopedic surgery

Identifiers

PMID41018295
PMCPMC12465096

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.